Hu Dongcai, Tie Kai, Yang Xiao, Tan Yang, Alaidaros Mohammed, Chen Liaobin
Department of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China.
Department of Intensive Care Unit, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, China.
J Orthop Surg Res. 2015 Feb 3;10:22. doi: 10.1186/s13018-015-0163-2.
In recent years, the choice of ceramic-on-ceramic (COC) and metal-on-polyethylene (MOP) in primary total hip arthroplasty (THA) remains controversial. The purpose of this study was to compare the reliability and durability of COC with that of MOP bearing surfaces in THA.
Based on prospective randomized controlled trials (RCTs) searched from Pubmed, Embase, Web of Science, and Cochrane central database, we performed a meta-analysis for comparing clinical and radiographic outcomes of COC with those of MOP. Two investigators independently selected studies, extracted data, and assessed risk of bias. Relative risks and weighted mean differences from each trial were pooled using random-effect or fixed-effect models depending on the heterogeneity of the included studies.
Five RCTs involving 897 patients with 974 hips met predetermined inclusion criteria. Our results demonstrated COC significantly decreased the risks of revision, osteolysis and radiolucent line, aseptic loosening, and dislocation and increased the risks of squeaking and intraoperative implant fracture compared with MOP. There was no significant difference between the two groups in postoperative hip function, deep infection, and heterotopic ossification.
Generally, despite more squeaking and intraoperative implant fracture, our findings support the use of COC bearing surface which has lower rates of revision, osteolysis and radiolucent line, aseptic loosening, and dislocation compared with MOP.
近年来,初次全髋关节置换术(THA)中陶瓷对陶瓷(COC)和金属对聚乙烯(MOP)的选择仍存在争议。本研究的目的是比较THA中COC与MOP承重面的可靠性和耐久性。
基于从PubMed、Embase、科学网和Cochrane中心数据库检索到的前瞻性随机对照试验(RCT),我们进行了一项荟萃分析,以比较COC与MOP的临床和影像学结果。两名研究人员独立选择研究、提取数据并评估偏倚风险。根据纳入研究的异质性,使用随机效应或固定效应模型汇总每个试验的相对风险和加权平均差异。
五项RCT涉及897例患者的974个髋关节,符合预定的纳入标准。我们的结果表明,与MOP相比,COC显著降低了翻修、骨溶解和透亮线、无菌性松动和脱位的风险,并增加了摩擦音和术中植入物骨折的风险。两组在术后髋关节功能、深部感染和异位骨化方面无显著差异。
总体而言,尽管摩擦音和术中植入物骨折较多,但我们的研究结果支持使用COC承重面,与MOP相比,其翻修、骨溶解和透亮线、无菌性松动和脱位的发生率较低。