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对于初次全髋关节置换术,陶瓷对陶瓷轴承真的比陶瓷对聚乙烯轴承更具优势吗?一项随机对照试验的系统评价和荟萃分析。

Is a ceramic-on-ceramic bearing really superior to ceramic-on-polyethylene for primary total hip arthroplasty? A systematic review and meta-analysis of randomised controlled trials.

作者信息

Si Hai-Bo, Zeng Yi, Cao Fei, Pei Fu-Xing, Shen Bin

机构信息

West China Hospital, Sichuan University, Sichuan Province - China.

出版信息

Hip Int. 2015 May-Jun;25(3):191-8. doi: 10.5301/hipint.5000223. Epub 2015 Feb 12.

DOI:10.5301/hipint.5000223
PMID:25684252
Abstract

INTRODUCTION

The outcomes of using a ceramic-on-ceramic (CoC) vs ceramic-on-polyethylene (CoP) bearing surface for primary total hip arthroplasty (THA) are much debated. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs) to compare and evaluate the outcomes of these 2 bearing surfaces.

MATERIALS AND METHODS

Electronic databases (PubMed/Medline, CENTRAL, Embase and Web of Science) were systematically searched for RCTs investigating the association between bearing surfaces and outcomes following primary THA. Two investigators independently reviewed studies for eligibility, assessed the risk of bias, extracted and analysed the data.

RESULTS

In total, 13 RCTs including a total of 2,488 THAs were identified. The Harris Hip Score appeared to be similar between CoC and CoP THAs. The acetabular liner wear rate was lower in CoC than CoP THA, but the meta-analysis showed that the incidence of component-related noise and overall ceramic fracture in CoC group were 14.73 times and 6.02 times higher than CoP THA, respectively. There were no statistically significant differences in rates of radiolucent line formation (>1 mm), osteolysis, loosening, revision with follow-up ≥ 5 years, intraoperative femoral fracture, dislocation, deep infection, deep venous thrombosis and leg length discrepancy between CoC and CoP THAs.

CONCLUSIONS

There appears to be no clear evidence favouring the use of either a CoC or CoP bearing surfaces in primary THA, further studies with high-quality and longer term follow-up to provide more evidence on this topic are still required.

摘要

引言

在初次全髋关节置换术(THA)中,使用陶瓷对陶瓷(CoC)与陶瓷对聚乙烯(CoP)关节面的效果存在诸多争议。我们对随机对照试验(RCT)进行了系统评价和荟萃分析,以比较和评估这两种关节面的效果。

材料与方法

系统检索电子数据库(PubMed/Medline、CENTRAL、Embase和Web of Science),查找研究初次THA后关节面与效果之间关联的RCT。两名研究者独立审查研究的合格性,评估偏倚风险,提取并分析数据。

结果

共识别出13项RCT,包括总计2488例THA。CoC和CoP全髋关节置换术的Harris髋关节评分似乎相似。CoC组的髋臼衬垫磨损率低于CoP组,但荟萃分析显示,CoC组与部件相关的噪音发生率和总体陶瓷骨折发生率分别比CoP组高14.73倍和6.02倍。在随访≥5年时,CoC和CoP全髋关节置换术在透亮线形成(>1mm)、骨溶解、松动、翻修、术中股骨骨折、脱位、深部感染、深静脉血栓形成和肢体长度差异发生率方面无统计学显著差异。

结论

在初次THA中,似乎没有明确证据支持使用CoC或CoP关节面,仍需要高质量和长期随访的进一步研究来提供关于该主题的更多证据。

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