Primer David N, Karakaya Idris, Tellis John C, Molander Gary A
Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6323, United States.
J Am Chem Soc. 2015 Feb 18;137(6):2195-8. doi: 10.1021/ja512946e. Epub 2015 Feb 4.
Single-electron-mediated alkyl transfer affords a novel mechanism for transmetalation, enabling cross-coupling under mild conditions. Here, general conditions are reported for cross-coupling of secondary alkyltrifluoroborates with an array of aryl bromides mediated by an Ir photoredox catalyst and a Ni cross-coupling catalyst.
单电子介导的烷基转移提供了一种新颖的金属转移机制，能够在温和条件下实现交叉偶联。在此，报道了由铱光氧化还原催化剂和镍交叉偶联催化剂介导的仲烷基三氟硼酸盐与一系列芳基溴化物交叉偶联的通用条件。
