延髓内侧损伤后出现无张力性快速眼动睡眠。
REM sleep without atonia after lesions of the medial medulla.
作者信息
Schenkel E, Siegel J M
机构信息
Neurobiology Research, Sepulveda V.A. Medical Center, CA 91343.
出版信息
Neurosci Lett. 1989 Mar 27;98(2):159-65. doi: 10.1016/0304-3940(89)90503-x.
Abstract
Rapid eye movement (REM) sleep is normally accompanied by a complete suppression of tone in the antigravity musculature. Pontine lesions have been shown to block this suppression, producing a syndrome of REM sleep without atonia. We now report that glutamate-induced lesions of the medial medulla, including the nucleus magnocellularis, caudal nucleus gigantocellularis and rostral nucleus paramedianus, produce REM sleep without atonia. These nuclei may function as part of a ponto-medullary system suppressing muscle tone in REM sleep.
摘要
快速眼动（REM）睡眠通常伴随着抗重力肌肉组织张力的完全抑制。已证明脑桥病变会阻断这种抑制，产生无张力性REM睡眠综合征。我们现在报告，谷氨酸诱导的延髓内侧病变，包括巨细胞大细胞核、尾侧巨细胞网状核和嘴侧旁正中核，会产生无张力性REM睡眠。这些核可能作为脑桥-延髓系统的一部分发挥作用，在REM睡眠中抑制肌肉张力。
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