Angiotensin II receptor blocker as a novel therapy in acute lung injury induced by avian influenza A H5N1 virus infection in mouse.
作者信息
Yan YiWu, Liu Qiang, Li Ning, Du JianChao, Li Xiao, Li Chang, Jin NingYi, Jiang ChengYu
机构信息
State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences; Department of Biochemistry and Molecular Biology, Peking Union Medical College, Tsinghua University, Beijing, 100005, China.
出版信息
Sci China Life Sci. 2015 Feb;58(2):208-11. doi: 10.1007/s11427-015-4814-7. Epub 2015 Feb 7.
Abstract
摘要
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Angiotensin II plasma levels are linked to disease severity and predict fatal outcomes in H7N9-infected patients.血管紧张素II血浆水平与H7N9感染患者的疾病严重程度相关，并可预测其致命结局。
Nat Commun. 2014 May 6;5:3595. doi: 10.1038/ncomms4595.
2
Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections.血管紧张素转换酶2可预防致死性甲型H5N1禽流感感染。
Nat Commun. 2014 May 6;5:3594. doi: 10.1038/ncomms4594.
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How will physicians respond to the next influenza pandemic?医生们将如何应对下一次流感大流行？
Clin Infect Dis. 2014 Jan;58(2):233-7. doi: 10.1093/cid/cit695. Epub 2013 Oct 21.
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Renin-angiotensin system blocking drugs.肾素-血管紧张素系统阻断药物
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Population-based study of statins, angiotensin II receptor blockers, and angiotensin-converting enzyme inhibitors on pneumonia-related outcomes.基于人群的他汀类药物、血管紧张素 II 受体阻滞剂和血管紧张素转换酶抑制剂与肺炎相关结局的研究。
Clin Infect Dis. 2012 Dec;55(11):1466-73. doi: 10.1093/cid/cis733. Epub 2012 Aug 23.
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Airborne transmission of influenza A/H5N1 virus between ferrets.雪貂之间甲型流感病毒 H5N1 的空气传播。
Science. 2012 Jun 22;336(6088):1534-41. doi: 10.1126/science.1213362.
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Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets.实验性改造的流感 H5 HA 可使重组 H5 HA/H1N1 病毒在雪貂中通过呼吸道飞沫传播。
Nature. 2012 May 2;486(7403):420-8. doi: 10.1038/nature10831.
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Innate immune responses to influenza A H5N1: friend or foe?流感 A H5N1 的先天免疫反应：是敌是友？
Trends Immunol. 2009 Dec;30(12):574-84. doi: 10.1016/j.it.2009.09.004. Epub 2009 Oct 26.
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The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice.血管紧张素转换酶2的发现及其在小鼠急性肺损伤中的作用。
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A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury.血管紧张素转换酶2（ACE2）在严重急性呼吸综合征冠状病毒诱导的肺损伤中的关键作用。
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