Mohammed Aminu Zakari, Edino Steven Tijjani, Umar Ali Bala
Department of Pathology, Aminu Kano Teaching Hospital, Kano, Nigeria.
Department of Surgery, Bayero University Kano, Aminu Kano Teaching Hospital, Kano, Nigeria.
Niger Med J. 2015 Jan-Feb;56(1):71-3. doi: 10.4103/0300-1652.149176.
We report a rare case of leiomyoma of the thyroid gland associated with psammoma bodies. The patient was a 9-year-old black African boy. Prior to this, only five cases of primary thyroid leiomyoma have been reported. Histologically, thyroid leiomyoma was characterised by bundles of spindle smooth muscle cells with blunt-ended nuclei. Psammoma bodies were widely distributed within the tumour. Immunohistochemistry showed positive immunoreactivity for smooth muscle actin, vimentin and desmin, but was negative for a cytokeratin cocktail. Further reports of similar cases is required to ascertain the clinical significance of this lesion.
我们报告了一例罕见的伴有砂粒体的甲状腺平滑肌瘤病例。患者是一名9岁的非洲黑人男孩。在此之前，仅报道过5例原发性甲状腺平滑肌瘤。组织学上，甲状腺平滑肌瘤的特征是成束的梭形平滑肌细胞，核呈钝端。砂粒体广泛分布于肿瘤内。免疫组织化学显示平滑肌肌动蛋白、波形蛋白和结蛋白免疫反应呈阳性，但细胞角蛋白混合物免疫反应呈阴性。需要更多类似病例的报告来确定该病变的临床意义。
