Johnson Noah R, Wang Yadong
320 Benedum Hall, 3700 O'Hara St, Pittsburgh, PA 15261 USA.
Curr Pharm Biotechnol. 2015;16(7):621-9. doi: 10.2174/1389201016666150206113720.
Protein, gene, and small molecule therapies hold great potential for facilitating comprehensive tissue repair and regeneration. However, their clinical value will rely on effective delivery systems which maximize their therapeutic benefit. Significant advances have been made in recent years towards biomaterial delivery systems to satisfy this clinical need. Here we summarize the most outstanding advances in drug delivery technology for cutaneous wound healing.
蛋白质、基因和小分子疗法在促进全面的组织修复和再生方面具有巨大潜力。然而,它们的临床价值将依赖于能使治疗效果最大化的有效递送系统。近年来,在满足这一临床需求的生物材料递送系统方面已取得显著进展。在此,我们总结了用于皮肤伤口愈合的药物递送技术中最突出的进展。