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用于伤口愈合的药物递送系统。

Drug delivery systems for wound healing.

作者信息

Johnson Noah R, Wang Yadong

机构信息

320 Benedum Hall, 3700 O'Hara St, Pittsburgh, PA 15261 USA.

出版信息

Curr Pharm Biotechnol. 2015;16(7):621-9. doi: 10.2174/1389201016666150206113720.

DOI:10.2174/1389201016666150206113720
PMID:25658378
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6053062/
Abstract

Protein, gene, and small molecule therapies hold great potential for facilitating comprehensive tissue repair and regeneration. However, their clinical value will rely on effective delivery systems which maximize their therapeutic benefit. Significant advances have been made in recent years towards biomaterial delivery systems to satisfy this clinical need. Here we summarize the most outstanding advances in drug delivery technology for cutaneous wound healing.

摘要

蛋白质、基因和小分子疗法在促进全面的组织修复和再生方面具有巨大潜力。然而,它们的临床价值将依赖于能使治疗效果最大化的有效递送系统。近年来,在满足这一临床需求的生物材料递送系统方面已取得显著进展。在此,我们总结了用于皮肤伤口愈合的药物递送技术中最突出的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ae/6053062/d722827022e2/nihms967359f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ae/6053062/d35486d3a235/nihms967359f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ae/6053062/d722827022e2/nihms967359f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ae/6053062/d35486d3a235/nihms967359f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48ae/6053062/d722827022e2/nihms967359f2.jpg

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本文引用的文献

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The Effect of Control-released Basic Fibroblast Growth Factor in Wound Healing: Histological Analyses and Clinical Application.控释碱性成纤维细胞生长因子在伤口愈合中的作用:组织学分析与临床应用
Plast Reconstr Surg Glob Open. 2013 Oct 7;1(6):e44. doi: 10.1097/GOX.0b013e3182a88787. eCollection 2013 Sep.
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Coacervate delivery systems for proteins and small molecule drugs.用于蛋白质和小分子药物的凝聚层递送系统。
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Development and bioevaluation of nanofibers with blood-derived growth factors for dermal wound healing.
大麻素在皮肤伤口护理中的应用:新兴临床前和临床证据的系统评价
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Recent advances in molecular mechanisms of skin wound healing and its treatments.皮肤创伤愈合及其治疗的分子机制的最新进展。
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Sustainable Silk-Based Particulate Systems for the Controlled Release of Pharmaceuticals and Bioactive Agents in Wound Healing and Skin Regeneration.可持续的基于丝素的微粒系统用于药物和生物活性物质在创伤愈合和皮肤再生中的控制释放。
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