Flanagan P G, Rooney P G, Davies E A, Stout R W
Department of Geriatric Medicine, Queen's University of Belfast.
Lancet. 1989 May 20;1(8647):1117-9. doi: 10.1016/s0140-6736(89)92392-1.
Four screening tests for bacteriuria were assessed at ward level in 418 elderly subjects and were compared with standard methods of bacterial culture. The tests were visual appearance; microscopy; dipstick for nitrite, leucocyte esterase, protein, and blood; and dipstick for nitrite and organisms. The sensitivity of the tests varied from 85.6% to 98.3%, and the specificity from 18.4% to 82.9%. A combination of visual appearance and dipstick testing for nitrite and leucocyte esterase gave a sensitivity of 96.1% with a specificity of 50.6%, and could have reduced by almost one-third the number of urine samples submitted to the laboratory for processing.
在病房层面,对418名老年受试者的四种菌尿筛查试验进行了评估,并与细菌培养的标准方法进行了比较。这些试验包括肉眼观察;显微镜检查;检测亚硝酸盐、白细胞酯酶、蛋白质和血液的试纸条;以及检测亚硝酸盐和微生物的试纸条。这些试验的敏感性从85.6%到98.3%不等,特异性从18.4%到82.9%不等。肉眼观察与检测亚硝酸盐和白细胞酯酶的试纸条检测相结合,敏感性为96.1%,特异性为50.6%,并且可以将提交到实验室进行处理的尿液样本数量减少近三分之一。