Pfaller M A, Koontz F P
J Clin Microbiol. 1985 May;21(5):840-2. doi: 10.1128/jcm.21.5.840-842.1985.
We compared the sensitivity, specificity, and predictive values of the 1-min leukocyte esterase test and the test for urinary nitrite alone and in combination as screening tests for bacteriuria in over 5,000 clinical urine specimens. The leukocyte esterase-nitrite combination had a sensitivity of 79.2%, a specificity of 81%, and a negative predictive value of a negative test of 94.5% for specimens with greater than or equal to 10(5) CFU/ml. Although the sensitivity of this test was too low to allow its use as the only screening test for bacteriuria, it may serve as a useful adjunct to culturing and other urine-processing systems in the microbiology laboratory.
我们比较了1分钟白细胞酯酶试验、单独的尿亚硝酸盐试验以及两者联合作为5000多份临床尿液标本中菌尿筛查试验的敏感性、特异性和预测值。对于菌落形成单位(CFU)/毫升大于或等于10⁵的标本,白细胞酯酶-亚硝酸盐联合试验的敏感性为79.2%,特异性为81%,阴性试验的阴性预测值为94.5%。尽管该试验的敏感性过低,不能作为菌尿的唯一筛查试验,但它可作为微生物实验室培养及其他尿液处理系统的有用辅助手段。