Weng Meilin, Zhu Minmin, Chen Wankun, Miao Changhong
Department of Anaesthesiology, Fudan University Shanghai Cancer Center No. 270 Dong'an Road, Shanghai 200032, China ; Department of Oncology, Shanghai Medical College, Fudan University No. 270 Dong'an Road, Shanghai 200032, China.
Int J Clin Exp Med. 2014 Dec 15;7(12):5930-6. eCollection 2014.
In this article, we report two life-threatening anaphylactic shocks by an antiseptic coated central venous catheter (CVC) within a 6-month period in our cancer center. Anaphylactic shock was preceded immediately after insertion of a central venous catheter (CVC) coated with silver sulphadiazine and chlorhexidine acetate (Blue FlexTip(®) ARROWg(+)ard Blue(®), 14Ga, Arrow International, Inc. USA). Though antiseptic coated CVC anaphylaxis has been reported in Japan, Europe and America, to our knowledge, this is first reported in China. We present these rare cases to remind clinicians about hypersensitivity to chlorhexidine that could potentially be life-threatening.
在本文中，我们报告了在我们癌症中心6个月内发生的两例因使用抗菌涂层中心静脉导管（CVC）引发的危及生命的过敏性休克。过敏性休克在插入涂有磺胺嘧啶银和醋酸氯己定的中心静脉导管（CVC）（Blue FlexTip(®) ARROWg(+)ard Blue(®)，14Ga，美国Arrow International公司）后立即发生。尽管在日本、欧洲和美国都有抗菌涂层CVC过敏反应的报道，但据我们所知，这是在中国首次报道。我们展示这些罕见病例，以提醒临床医生注意对氯己定的过敏反应，这种反应可能会危及生命。
