Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
Danish Anaesthesia Allergy Centre, Allergy Clinic, Department of Dermatology and Allergy, Copenhagen University Hospital Gentofte, Kildegårdsvej 28, 2900, Hellerup, Denmark.
Curr Allergy Asthma Rep. 2019 Mar 14;19(5):23. doi: 10.1007/s11882-019-0858-2.
In recent years, the risk of allergy to chlorhexidine is increasingly recognised. In this review, we discuss why the allergy is so easily overlooked and point out several preventative initiatives that can minimise the risk of both chlorhexidine sensitisation and allergy development and accidental re-exposure in patients with chlorhexidine allergy. Testing for chlorhexidine allergy is also discussed.
Numerous reports have been published from many different specialties. Symptoms range from mild skin symptoms to life-threatening anaphylaxis. Testing for chlorhexidine allergy is based on skin testing and in vitro testing. Recently, it was found that both skin prick testing and specific IgE have high sensitivities and specificities. This review gives an overview of chlorhexidine allergy with a special focus on preventative initiatives and testing.
近年来，人们越来越认识到氯己定过敏的风险。在这篇综述中，我们讨论了为什么这种过敏很容易被忽视，并指出了一些预防措施，可以最大限度地降低氯己定致敏和过敏发展的风险，并防止氯己定过敏患者意外再次暴露。我们还讨论了氯己定过敏的检测。
来自许多不同专业的大量报告已经发表。症状从轻度皮肤症状到危及生命的过敏反应不等。氯己定过敏的检测基于皮肤试验和体外试验。最近发现，皮肤点刺试验和特异性 IgE 均具有较高的敏感性和特异性。本综述概述了氯己定过敏，特别关注预防措施和检测。
