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旁遮普邦西北部人群维生素D缺乏症的患病率:一项横断面研究。

Prevalence of vitamin D deficiency in north-west Punjab population: A cross-sectional study.

作者信息

Bachhel Rachna, Singh Navyug Raj, Sidhu Jagtesh Singh

机构信息

Department of Physiology, Government Medical College, Amritsar, Punjab, India.

Department of Pharmacology, Government Medical College, Amritsar, Punjab, India.

出版信息

Int J Appl Basic Med Res. 2015 Jan-Apr;5(1):7-11. doi: 10.4103/2229-516X.149220.

Abstract

BACKGROUND

Many studies show a high prevalence of vitamin D deficiency across various populations the world over. There is relative lack of prevalence data in Punjab, India. This cross-sectional study was carried out to assess the prevalence of vitamin D deficiency in the north-west Punjab population.

AIM

To study the prevalence of vitamin D deficiency in the north-west Punjab population across various population characteristics such as gender, education, locality, occupation, and dietary habits.

MATERIALS AND METHODS

Healthy volunteers (N = 150) of either sex were enrolled and their fasting plasma samples tested for 25-hydroxy vitamin D [25(OH) D] levels. Data were compiled as percentages and means across different population characteristics. Statistical analysis was done using Chi-square test and Fisher's exact test.

RESULTS

A high overall prevalence (90%) of vitamin D deficiency was observed in the study subjects. There was a significant difference in the prevalence of vitamin D insufficiency between rural and urban subjects (P < 0.05) and among the subjects pursuing different occupations (P < 0.001). A significant gender-specific difference was also recorded at the cut-off level of 25 (OH) D, with women showing higher prevalence of deficiency compared to men (P < 0.05).

CONCLUSIONS

There is a high prevalence of vitamin D deficiency in the population of Punjab. Lower prevalence is displayed by those subjects who have greater opportunities for sunlight exposure, such as like rural individuals, farmers, and housewives.

摘要

背景

许多研究表明,全球不同人群中维生素D缺乏症的患病率很高。印度旁遮普邦相对缺乏患病率数据。本横断面研究旨在评估旁遮普邦西北部人群中维生素D缺乏症的患病率。

目的

研究旁遮普邦西北部人群中维生素D缺乏症的患病率,涉及不同人口特征,如性别、教育程度、居住地点、职业和饮食习惯。

材料与方法

招募了150名健康的志愿者(男女不限),并对他们的空腹血浆样本进行25-羟基维生素D [25(OH)D]水平检测。数据以不同人口特征的百分比和均值形式汇总。采用卡方检验和Fisher精确检验进行统计分析。

结果

研究对象中维生素D缺乏症的总体患病率很高(90%)。农村和城市受试者之间以及从事不同职业的受试者之间维生素D不足的患病率存在显著差异(P < 0.05)。在25(OH)D的临界水平上,还记录到了显著的性别差异,女性的缺乏患病率高于男性(P < 0.05)。

结论

旁遮普邦人群中维生素D缺乏症的患病率很高。那些有更多阳光照射机会的受试者,如农村居民、农民和家庭主妇,患病率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7dd/4318108/1fbcf8dcbf10/IJABMR-5-7-g002.jpg

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