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软骨修复的生物增强:富血小板血浆及其他市售生长因子的作用。

Biologic enhancement of cartilage repair: the role of platelet-rich plasma and other commercially available growth factors.

作者信息

Cugat Ramon, Cuscó Xavier, Seijas Roberto, Álvarez Pedro, Steinbacher Gilbert, Ares Oscar, Wang-Saegusa Ana, García-Balletbó Montserrat

机构信息

Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Mutualidad de Futbolistas, Royal Spanish Football Federation, Barcelona, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain.

Division of Medicine and Regenerative Surgery, Garcia Cugat Foundation and CEU Cardenal Herrera University, Valencia, Spain; Department of Orthopaedic Surgery, Sports Medicine and Trauma, Hospital Quiron Barcelona, Barcelona, Spain.

出版信息

Arthroscopy. 2015 Apr;31(4):777-83. doi: 10.1016/j.arthro.2014.11.031. Epub 2015 Feb 7.

DOI:10.1016/j.arthro.2014.11.031
PMID:25670338
Abstract

In part, people's quality of life depends on the "health" of their cartilage because its damage or deterioration causes pain that limits mobility and reduces autonomy. Predisposing genetic factors and modern-life environmental factors, such as diet, excessive physical exercise, or the absence of any physical exercise, in addition to injuries that can occur, all contribute to the onset and development of chronic degenerative diseases such as osteoarthritis. Regenerative medicine focuses on the repair, replacement, or regeneration of cells, tissues, or organs to restore impaired function from any cause, including congenital defects, disease, and trauma.

摘要

在一定程度上,人们的生活质量取决于其软骨的“健康状况”,因为软骨损伤或退化会引发疼痛,限制行动能力并降低自主性。除了可能发生的损伤外,遗传易感性因素和现代生活环境因素,如饮食、过度体育锻炼或缺乏体育锻炼,都促成了骨关节炎等慢性退行性疾病的发生和发展。再生医学专注于细胞、组织或器官的修复、替换或再生,以恢复因任何原因(包括先天性缺陷、疾病和创伤)受损的功能。

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