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中国33个社区城市成年人代谢综合征及心血管相关危险因素患病率的性别差异:CHPSNE研究

Sex difference in the prevalence of metabolic syndrome and cardiovascular-related risk factors in urban adults from 33 communities of China: The CHPSNE study.

作者信息

Song Qing-Bin, Zhao Yang, Liu Yu-Qin, Zhang Jian, Xin Shi-Jie, Dong Guang-Hui

机构信息

Department of General Surgery, The First Affiliated Hospital of China Medical University, Shenyang, People's Republic of China

Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, People's Republic of China.

出版信息

Diab Vasc Dis Res. 2015 May;12(3):189-98. doi: 10.1177/1479164114562410. Epub 2015 Feb 9.

DOI:10.1177/1479164114562410
PMID:25670848
Abstract

Little is known about the epidemiology of metabolic syndrome in urban areas of China. To estimate the prevalence of MetS and identify its cardiovascular-related factors in men and women, a representative sample of 15,477 urban adults aged 18-74 years in Northeast China was selected from 2009 to 2010. The diagnosis of metabolic syndrome was based on criteria set by the National Cholesterol Education Program/Adult Treatment Panel. The overall prevalence of metabolic syndrome was 27.4% (men 27.9% and women 26.8%). Multivariable logistic regression analysis revealed that a higher education level and a higher family income were associated with a higher prevalence of metabolic syndrome in men, but associated with lower prevalence of metabolic syndrome among women. Higher physical activity was associated with a decreased prevalence of metabolic syndrome in men (adjusted odds ratios (aORs) = 0.88, 95% confidence interval (CI): 0.79-0.99), but associated with an increased prevalence of metabolic syndrome in women (aOR = 1.14, 95% CI: 1.00-1.29). Compared with rice as the major staple food, cooked wheaten foods were associated with lower adjusted odds for metabolic syndrome both in men (aOR = 0.72, 95% CI: 0.58-0.90) and in women (aOR = 0.72, 95% CI: 0.56-0.92). In conclusion, metabolic syndrome is highly prevalent in urban areas of China, and there is heterogeneity by sex in the relationships between risk factors and metabolic syndrome prevalence.

摘要

中国城市地区代谢综合征的流行病学情况鲜为人知。为了估计代谢综合征的患病率并确定其在男性和女性中与心血管相关的因素,2009年至2010年从中国东北地区选取了15477名年龄在18 - 74岁的城市成年人作为代表性样本。代谢综合征的诊断基于美国国家胆固醇教育计划/成人治疗小组设定的标准。代谢综合征的总体患病率为27.4%(男性为27.9%,女性为26.8%)。多变量逻辑回归分析显示,较高的教育水平和较高的家庭收入与男性代谢综合征患病率较高相关,但与女性代谢综合征患病率较低相关。较高的身体活动与男性代谢综合征患病率降低相关(调整后的优势比(aORs)= 0.88,95%置信区间(CI):0.79 - 0.99),但与女性代谢综合征患病率增加相关(aOR = 1.14,95% CI:1.00 - 1.29)。与以大米为主食相比,面食与男性(aOR = 0.72,95% CI:0.58 - 0.90)和女性(aOR = 0.72,95% CI:0.56 - 0.92)代谢综合征调整后的较低优势比相关。总之,代谢综合征在中国城市地区高度流行,危险因素与代谢综合征患病率之间的关系存在性别差异。

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