Sheridan R, Llerena J, Matkins S, Debenham P, Cawood A, Bobrow M
Division of Medical and Molecular Genetics, United Medical School, Guy's Hospital, London.
J Med Genet. 1989 May;26(5):294-8. doi: 10.1136/jmg.26.5.294.
We review the published reports on reproduction in cases of non-mosaic trisomy 21 (Down's syndrome) and present the first fully documented case of a non-mosaic male with Down's syndrome fathering a pregnancy, a fact which has important implications in the light of caring for these people in the community.
我们回顾了已发表的关于非嵌合型21三体综合征(唐氏综合征)患者生殖情况的报告,并呈现了首例有充分记录的非嵌合型唐氏综合征男性使女方受孕的病例,鉴于在社区中照顾这些患者,这一事实具有重要意义。