IEEE J Biomed Health Inform. 2016 Mar;20(2):624-30. doi: 10.1109/JBHI.2015.2399502. Epub 2015 Feb 6.
Wireless capsule endoscopy (WCE) enables noninvasive and painless direct visual inspection of a patient's whole digestive tract, but at the price of long time reviewing large amount of images by clinicians. Thus, an automatic computer-aided technique to reduce the burden of physicians is highly demanded. In this paper, we propose a novel color feature extraction method to discriminate the bleeding frames from the normal ones, with further localization of the bleeding regions. Our proposal is based on a twofold system. First, we make full use of the color information of WCE images and utilize K-means clustering method on the pixel represented images to obtain the cluster centers, with which we characterize WCE images as words-based color histograms. Then, we judge the status of a WCE frame by applying the support vector machine (SVM) and K-nearest neighbor methods. Comprehensive experimental results reveal that the best classification performance is obtained with YCbCr color space, cluster number 80 and the SVM. The achieved classification performance reaches 95.75% in accuracy, 0.9771 for AUC, validating that the proposed scheme provides an exciting performance for bleeding classification. Second, we propose a two-stage saliency map extraction method to highlight bleeding regions, where the first-stage saliency map is created by means of different color channels mixer and the second-stage saliency map is obtained from the visual contrast. Followed by an appropriate fusion strategy and threshold, we localize the bleeding areas. Quantitative as well as qualitative results show that our methods could differentiate the bleeding areas from neighborhoods correctly.
无线胶囊内镜(WCE)使临床医生能够非侵入性、无痛地直接观察患者的整个消化道,但代价是需要花费很长时间来审查大量的图像。因此,人们非常需要一种自动的计算机辅助技术来减轻医生的负担。在本文中,我们提出了一种新颖的颜色特征提取方法,用于区分出血帧和正常帧,并进一步定位出血区域。我们的方法基于一个双重系统。首先,我们充分利用 WCE 图像的颜色信息,并在像素表示图像上使用 K-均值聚类方法获得聚类中心,用这些聚类中心来描述 WCE 图像的基于单词的颜色直方图。然后,我们应用支持向量机(SVM)和 K-最近邻方法来判断 WCE 帧的状态。全面的实验结果表明,在 YCbCr 颜色空间、聚类数 80 和 SVM 下,分类性能最佳。准确率达到 95.75%,AUC 为 0.9771,验证了所提出的方案在出血分类方面提供了令人兴奋的性能。其次,我们提出了一种两阶段显著图提取方法来突出出血区域,其中第一阶段显著图是通过不同颜色通道的混合器创建的,第二阶段显著图是从视觉对比度中获得的。然后通过适当的融合策略和阈值,我们定位出血区域。定量和定性结果表明,我们的方法可以正确地区分出血区域和周围区域。