Li X F
Zhonghua Liu Xing Bing Xue Za Zhi. 1989 Feb;10(1):14-7.
Virulence between virus strains of hemorrhagic fever with renal syndrome (HFRS) from R. norvegicus and A. agrarius were different, besides the diversity in their epidemiological feature, clinical symptoms and antigenicity. Virulence of the virus strains from R. norvegicus, especially those from nonepidemic areas, were weak than those from A. agrarius. Sucking mice might be used for determining virulence of the virus strains from various source. Foci of HFRS had been in southern Fujian, but human cases of HFRS had rarely been found, or only a few mild cases were found in a few areas. This might be related to weaker virulence of the virus strains from R. norvegicus. The prevalent degree of the disease might be related to HFRSV of wild rattus type in the area.
肾综合征出血热（HFRS）褐家鼠型和黑线姬鼠型病毒株之间除了在流行病学特征、临床症状和抗原性方面存在差异外，其毒力也有所不同。褐家鼠型病毒株，尤其是非疫区的病毒株，毒力比黑线姬鼠型病毒株弱。乳鼠可用于测定不同来源病毒株的毒力。福建南部曾有HFRS疫源地，但很少发现HFRS病例，或仅在少数地区发现少数轻症病例。这可能与褐家鼠型病毒株毒力较弱有关。该病的流行程度可能与该地区野鼠型HFRSV有关。
