Dörfler Jaika, Preuss Till, Brahms Christian, Scheuer Dennis, Doye Sven
Institut für Chemie, Universität Oldenburg, Carl-von-Ossietzky-Strasse 9-11, D-26111 Oldenburg, Germany.
Dalton Trans. 2015 Jul 21;44(27):12149-68. doi: 10.1039/c4dt03916e.
An easily accessible formamidinate ligand-bearing titanium complex initially synthesized by Eisen et al. is used as catalyst for intermolecular hydroaminoalkylation reactions of unactivated, sterically demanding 1,1- and 1,2-disubstituted alkenes and styrenes with secondary amines. The corresponding reactions, which have never been achieved with titanium catalysts before, take place with excellent regioselectivity (up to 99 : 1) and in addition, corresponding reactions of 1,3-butadienes with N-methylbenzylamine are also described for the first time.
艾森等人最初合成的一种易于获取的含脒基配体的钛配合物被用作催化剂，用于未活化的、空间位阻较大的1,1-和1,2-二取代烯烃以及苯乙烯与仲胺的分子间氢氨烷基化反应。以前用钛催化剂从未实现过的相应反应，以优异的区域选择性（高达99:1）进行，此外，还首次描述了1,3-丁二烯与N-甲基苄胺的相应反应。
