Bergbrant I M, Faergemann J
Department of Dermatology, University of Gothenburg, Sahlgren's Hospital, Göteborg, Sweden.
Acta Derm Venereol. 1989;69(4):332-5.
Seborrhoeic dermatitis is associated with Pityrosporum ovale, but the exact role of the organism is not clarified. In order to study this connection we have investigated 30 patients with seborrhoeic dermatitis with quantitative culture for P. ovale, serum IgG antibodies against P. ovale and lipid measurements. We compared the patients with 60 healthy individuals and found no significant difference in the number of P. ovale or serum antibodies. The lipid content on the skin was significantly higher in the patient group (p = 0.0001). There was no difference in the number of P. ovale in lesions compared to healthy skin in the patient group. This study support our theory that an abnormal reaction in the skin to P. ovale causes the inflammation and the number of P. ovale is of minor importance.
脂溢性皮炎与卵圆形糠秕孢子菌有关，但该微生物的确切作用尚不清楚。为了研究这种关联，我们对30例脂溢性皮炎患者进行了卵圆形糠秕孢子菌定量培养、抗卵圆形糠秕孢子菌血清IgG抗体检测及脂质测量。我们将这些患者与60名健康个体进行比较，发现卵圆形糠秕孢子菌数量或血清抗体方面无显著差异。患者组皮肤脂质含量显著更高（p = 0.0001）。患者组皮损处卵圆形糠秕孢子菌数量与健康皮肤相比无差异。这项研究支持了我们的理论，即皮肤对卵圆形糠秕孢子菌的异常反应导致炎症，而卵圆形糠秕孢子菌数量的重要性较小。
