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因摄入洗手液继发的复发性乳酸酸中毒。

Recurrent lactic acidosis secondary to hand sanitizer ingestion.

作者信息

Wilson M E, Guru P K, Park J G

机构信息

Department of Internal Medicine, Division of Pulmonary and Critical Care, Mayo Clinic, Rochester, MN, USA.

出版信息

Indian J Nephrol. 2015 Jan-Feb;25(1):57-9. doi: 10.4103/0971-4065.135351.

DOI:10.4103/0971-4065.135351
PMID:25684875
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4323915/
Abstract

Due to their ability to decrease the spread of infection, hand sanitizers are now ubiquitous in health care settings. We present the case of a 50-year-old woman who was admitted with acute alcohol intoxication and had near complete recovery in 12 hrs. Subsequently, she was found unresponsive on the floor of her hospital room on two separate occasions. Evaluations revealed repeatedly elevated levels of ethanol, acetone, and lactate as well as increased anion gap and hypotension, requiring intensive care unit evaluation and intubation for airway protection. During the second episode, she was found next to an empty bottle of ethanol-based hospital hand sanitizer. She confirmed ingesting hand sanitizer in order to become intoxicated.

摘要

由于能够减少感染传播,洗手液如今在医疗环境中随处可见。我们报告一例50岁女性病例,该患者因急性酒精中毒入院,12小时内几乎完全康复。随后,她在医院病房的地板上被发现失去反应,且出现过两次这种情况。检查发现其乙醇、丙酮和乳酸水平反复升高,阴离子间隙增加,血压降低,需要重症监护病房评估并进行插管以保护气道。在第二次发作期间,她被发现在一瓶空的医院用乙醇基洗手液旁边。她承认摄入洗手液以达到醉酒状态。

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引用本文的文献

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Excessive use of disinfectants against COVID-19 posing a potential threat to living beings.过度使用针对新冠病毒的消毒剂对生物构成潜在威胁。
Curr Res Toxicol. 2021;2:159-168. doi: 10.1016/j.crtox.2021.02.008. Epub 2021 Mar 4.
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Sci Total Environ. 2020 Nov 10;742:140561. doi: 10.1016/j.scitotenv.2020.140561. Epub 2020 Jun 27.
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Intentional ingestion of hand sanitizer in an adult psychiatric unit.一名成年精神科病房患者故意摄入洗手液。
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本文引用的文献

1
The rising incidence of intentional ingestion of ethanol-containing hand sanitizers.有意摄入含乙醇的手部消毒剂导致发病率上升。
Crit Care Med. 2012 Jan;40(1):290-4. doi: 10.1097/CCM.0b013e31822f09c0.
2
Acute ethanol poisoning in a 4-year-old as a result of ethanol-based hand-sanitizer ingestion.一名4岁儿童因摄入含酒精的洗手液导致急性酒精中毒。
Pediatr Emerg Care. 2010 Jul;26(7):508-9. doi: 10.1097/PEC.0b013e3181e5bfc9.
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Acute alcohol intoxication.急性酒精中毒
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Ingestion of hand sanitizer by a hospitalized patient with a history of alcohol abuse.一名有酗酒史的住院患者摄入了洗手液。
Am J Health Syst Pharm. 2008 Dec 1;65(23):2203-4. doi: 10.2146/ajhp080320.
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Alcohol hand rubs: hygiene and hazard.酒精擦手液:卫生与危害
BMJ. 2007 Dec 1;335(7630):1154-5. doi: 10.1136/bmj.39274.583472.AE.
6
Changing dispensers may prevent intoxication from isopropanol and ethyl alcohol-based hand sanitizers.更换洗手液瓶可能会防止因使用异丙醇和乙醇类洗手液而导致中毒。
Ann Emerg Med. 2007 Oct;50(4):486. doi: 10.1016/j.annemergmed.2007.04.031.
7
Intoxication of a prison inmate with an ethyl alcohol-based hand sanitizer.一名监狱囚犯因使用含乙醇的洗手液而中毒。
N Engl J Med. 2007 Feb 1;356(5):529-30. doi: 10.1056/NEJMc063110.
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MMWR Recomm Rep. 2002 Oct 25;51(RR-16):1-45, quiz CE1-4.
9
Isopropyl alcohol intoxication: a diagnostic challenge.异丙醇中毒:一项诊断挑战。
Am J Kidney Dis. 2002 Sep;40(3):E12. doi: 10.1053/ajkd.2002.34938.
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Metadoxine in acute alcohol intoxication: a double-blind, randomized, placebo-controlled study.美他多辛治疗急性酒精中毒:一项双盲、随机、安慰剂对照研究。
Alcohol Clin Exp Res. 2002 Mar;26(3):340-6.