Department of Statistical Simulation, St. Petersburg State University, St. Petersburg, Russia, Illumina Cambridge, Cambridge, UK, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands, Department of Medical Genetics, Institute for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands and Department of Nematology, Wageningen University, Wageningen, The Netherlands.
Department of Statistical Simulation, St. Petersburg State University, St. Petersburg, Russia, Illumina Cambridge, Cambridge, UK, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands, Department of Medical Genetics, Institute for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands and Department of Nematology, Wageningen University, Wageningen, The Netherlands Department of Statistical Simulation, St. Petersburg State University, St. Petersburg, Russia, Illumina Cambridge, Cambridge, UK, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands, Department of Medical Genetics, Institute for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands and Department of Nematology, Wageningen University, Wageningen, The Netherlands.
Bioinformatics. 2015 Jun 15;31(12):2032-4. doi: 10.1093/bioinformatics/btv098. Epub 2015 Feb 19.
Sambamba is a high-performance robust tool and library for working with SAM, BAM and CRAM sequence alignment files; the most common file formats for aligned next generation sequencing data. Sambamba is a faster alternative to samtools that exploits multi-core processing and dramatically reduces processing time. Sambamba is being adopted at sequencing centers, not only because of its speed, but also because of additional functionality, including coverage analysis and powerful filtering capability.
Sambamba is free and open source software, available under a GPLv2 license. Sambamba can be downloaded and installed from http://www.open-bio.org/wiki/Sambamba.Sambamba v0.5.0 was released with doi:10.5281/zenodo.13200.
Sambamba 是一个高性能、强大的工具和库,用于处理 SAM、BAM 和 CRAM 序列比对文件;这些是对齐的下一代测序数据最常见的文件格式。Sambamba 是 samtools 的一个更快的替代品,它利用多核处理,并大大减少处理时间。Sambamba 正在测序中心被采用,不仅因为它的速度,还因为它的附加功能,包括覆盖分析和强大的过滤能力。
Sambamba 是免费的开源软件,根据 GPLv2 许可证授权。可以从 http://www.open-bio.org/wiki/Sambamba 下载和安装 Sambamba。Sambamba v0.5.0 已发布,doi:10.5281/zenodo.13200。