Bogod D G, Oh T E
Chinese University of Hong Kong, Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, Shatin, New Territories.
Anaesthesia. 1989 Jul;44(7):591-3. doi: 10.1111/j.1365-2044.1989.tb11451.x.
Fifteen patients who underwent elective Caesarean section were given sodium citrate, either alone or combined with oral cimetidine or ranitidine, as antacid premedication. No significant differences in time to 25 or 50% recovery of the first twitch of a train-of-four after administration of suxamethonium were found between any of the groups. It is concluded that H2-antagonists do not significantly affect the duration of action of suxamethonium in parturients, in contrast to the findings of a study in nonpregnant patients.
15例行择期剖宫产的患者接受了柠檬酸钠治疗，单独使用或与口服西咪替丁或雷尼替丁联合使用，作为抗酸药进行术前用药。在任何一组中，给予琥珀胆碱后，四个成串刺激中第一个肌颤搐恢复到25%或50%的时间均无显著差异。得出的结论是，与一项针对非妊娠患者的研究结果相反，H2拮抗剂对产妇琥珀胆碱的作用持续时间没有显著影响。
