James M F, Cork R C, Dennett J E
Anesth Analg. 1986 Apr;65(4):373-6.
The effect of pretreatment with 60 mg/kg magnesium sulfate on the neuromuscular blockade and consequent potassium release produced by 1.5 mg/kg succinylcholine in ten normal patients was compared with ten saline pretreated control patients. Magnesium had no significant effect on the characteristics of the paralysis. In control patients, serum potassium increased by an average of 0.57 +/- 0.20 (SEM) mmol/L. No patient in the magnesium group had an increase in serum potassium (mean change -0.05 +/- 0.02 mmol/L). The difference between the groups was statistically significant (P less than 0.01).
将10例正常患者中60mg/kg硫酸镁预处理对1.5mg/kg琥珀酰胆碱所致神经肌肉阻滞及随后钾释放的影响，与10例生理盐水预处理的对照患者进行比较。镁对麻痹特征无显著影响。在对照患者中，血清钾平均升高0.57±0.20（SEM）mmol/L。镁组患者血清钾均未升高（平均变化-0.05±0.02mmol/L）。两组间差异具有统计学意义（P＜0.01）。
