Department of Chemistry and Nano Science (BK 21 Plus), Ewha Womans University, 120-750 Seoul, Korea.
Chem Soc Rev. 2015 Apr 21;44(8):2489-507. doi: 10.1039/c4cs00430b.
The design and implementation of tandem reactions provides organic chemists with numerous challenges, in particular that of undesired cross-reactivity between substrates. Among organometallics, the use of organozinc reagents in tandem reactions provides several advantages as a result of their broad functional group tolerance and compatibility with transition metals. This review highlights prominent examples of recent advances in tandem reactions with organozinc reagents that illustrate their potential in organic synthesis.
串联反应的设计和实施给有机化学家带来了诸多挑战，尤其是底物之间不希望发生的交叉反应。在有机金属中，由于其对官能团的广泛耐受性以及与过渡金属的兼容性，有机锌试剂在串联反应中的应用具有许多优势。本文综述了近年来利用有机锌试剂进行串联反应的突出实例，说明了其在有机合成中的潜力。
