York Trials Unit, Department of Health Sciences, Heslington University of York, York YO10 5DD, UK.
York Trials Unit, Department of Health Sciences, Heslington University of York, York YO10 5DD, UK.
J Clin Epidemiol. 2015 Dec;68(12):1446-50. doi: 10.1016/j.jclinepi.2015.01.016. Epub 2015 Jan 27.
To assess the effectiveness of sending electronic prompts to randomized controlled trial participants to return study questionnaires.
A "trial within a trial" embedded within a study determining the effectiveness of chronic obstructive pulmonary disease (DOC) screening on smoking cessation. Those participants taking part in DOC who provided a mobile phone number and/or an electronic mail address were randomized to either receive an electronic prompt or no electronic prompt to return a study questionnaire. The results were combined with two previous studies in a meta-analysis.
A total of 437 participants were randomized: 226 to the electronic prompt group and 211 to the control group. A total of 285 (65.2%) participants returned the follow-up questionnaire: 157 (69.5%) in the electronic prompt group and 128 (60.7%) in the control group [difference 8.8%; 95% confidence interval (CI): -0.11%, 17.7%; P = 0.05]. The mean time to response was 23 days in the electronic prompt group and 33 days in the control group (hazard ratio = 1.27; 95% CI: 1.105, 1.47). The meta-analysis of all three studies showed an increase in response rate of 7.1% (95% CI: 0.8%, 13.3%).
The use of electronic prompts increased response rates and reduces the time to response.
评估向随机对照试验参与者发送电子提示以返回研究问卷的效果。
一项“嵌套试验”，嵌入在一项关于慢性阻塞性肺疾病（DOC）筛查对戒烟效果的研究中。那些参与 DOC 并提供手机号码和/或电子邮件地址的参与者被随机分配到接受电子提示或不接受电子提示以返回研究问卷的组。结果与之前的两项研究进行了荟萃分析。
共有 437 名参与者被随机分配：226 名进入电子提示组，211 名进入对照组。共有 285 名（65.2%）参与者返回了随访问卷：电子提示组 157 名（69.5%），对照组 128 名（60.7%）[差异 8.8%；95%置信区间（CI）：-0.11%，17.7%；P=0.05]。电子提示组的平均回复时间为 23 天，对照组为 33 天（风险比=1.27；95%CI：1.105，1.47）。对所有三项研究的荟萃分析显示，回复率增加了 7.1%（95%CI：0.8%，13.3%）。
使用电子提示提高了回复率并缩短了回复时间。
