York Trials Unit, University of York, York, UK.
F1000Res. 2020 Feb 26;9:154. doi: 10.12688/f1000research.22361.1. eCollection 2020.
: Research outcome data is commonly collected using postal questionnaires; however, poor response can introduce bias and reduce statistical power. Text messaging is simple, cost-effective, and can be customised to the individual. Personalised, reminder text messages may improve response rates. : A two-arm, parallel group 'Study within a Trial' (SWAT) was embedded within the Occupational Therapist Intervention Study (OTIS), a randomised controlled trial of a home assessment for falls prevention in older people. OTIS participants who provided a mobile phone number were randomly allocated (1:1) to receive either a personalised text message (Title, Surname, plus York Trials Unit (YTU) text) or the standard YTU text alone, prior to receiving their four-month post-randomisation follow-up postal questionnaire. The primary outcome measure was the proportion of participants who returned the questionnaire. Secondary outcomes were: time to response, completeness of response, requirement of a reminder letter, and cost-effectiveness. Binary data were compared using logistic regression and time to response by Cox proportional hazards regression. : A total of 403 participants were randomised: 201 to the personalised text and 202 to the standard text. Of the 283 participants included in the final analysis, 278 (98.2%) returned their questionnaire; 136 (97.8%) for the personalised text versus 142 (98.6%) for the standard text (adjusted odds ratio 0.64, 95% CI 0.10 to 3.88, p=0.63). The median time to response was nine days in both groups. In total, 271 (97.5%) participants returned a complete questionnaire; 133 (97.8%) in the personalised text versus 138 (97.2%) for the standard text. In total, 21 reminder letters were sent. The additional cost of personalised text messages was £0.04 per participant retained. : Personalised texts were not superior to standard texts in any outcome assessed in our study. Further SWATs are needed to perform a meta-analysis and obtain more evidence. : ISRCTN22202133; SWAT 35.
研究结果数据通常通过邮寄问卷收集，但低应答率可能会引入偏倚并降低统计效力。短信简单、经济高效，并且可以针对个人进行定制。个性化的提醒短信可能会提高回复率。
在一项针对老年人家庭跌倒预防的家庭评估的随机对照试验（OTIS）中，嵌入了一项双臂平行组“试验内研究”（SWAT）。OTIS 参与者提供手机号码后，将随机分配（1:1）接受个性化短信（姓名，姓氏，加上约克试验单位（YTU）文本）或仅接受标准 YTU 文本，然后再收到他们四个月的随机化后随访邮寄问卷。主要结局测量是返回问卷的参与者比例。次要结局是：响应时间，响应完整性，提醒信要求和成本效益。使用逻辑回归比较二进制数据，并使用 Cox 比例风险回归比较响应时间。
共有 403 名参与者被随机分配：201 名接受个性化短信，202 名接受标准短信。在最终分析中，283 名参与者中，278 名（98.2%）返回了问卷；136 名（97.8%）接受个性化短信，142 名（98.6%）接受标准短信（调整后的优势比 0.64，95%CI 0.10 至 3.88，p=0.63）。两组的中位响应时间均为九天。共有 271 名（97.5%）参与者返回完整的问卷；133 名（97.8%）接受个性化短信，138 名（97.2%）接受标准短信。共发送了 21 封提醒信。个性化短信的额外成本为每位参与者保留 0.04 英镑。
个性化短信在我们的研究中评估的任何结局上都不比标准短信优越。需要进一步的 SWAT 进行荟萃分析并获得更多证据。
ISRCTN22202133；SWAT 35。
