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A general mechanism for microsomal activation of quinone anticancer agents to free radicals.

作者信息

Bachur N R, Gordon S L, Gee M V

出版信息

Cancer Res. 1978 Jun;38(6):1745-50.

PMID:25710
Abstract
摘要

相似文献

1
A general mechanism for microsomal activation of quinone anticancer agents to free radicals.醌类抗癌剂经微粒体激活生成自由基的一般机制。
Cancer Res. 1978 Jun;38(6):1745-50.
2
Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation.蒽环类抗生素对微粒体电子传递和自由基形成的增强作用。
Mol Pharmacol. 1977 Sep;13(5):901-10.
3
NADPH cytochrome P-450 reductase activation of quinone anticancer agents to free radicals.NADPH细胞色素P-450还原酶将醌类抗癌剂激活为自由基。
Proc Natl Acad Sci U S A. 1979 Feb;76(2):954-7. doi: 10.1073/pnas.76.2.954.
4
Oxygen consumption and oxyradical production from microsomal reduction of aqueous extracts of cigarette tar.香烟焦油水提取物微粒体还原过程中的耗氧量和氧自由基生成量。
Arch Biochem Biophys. 1993 Aug 1;304(2):371-8. doi: 10.1006/abbi.1993.1364.
5
Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics.通过丝裂霉素类抗生素的生物活化产生活性氧自由基。
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6
[Adrenaline oxidation by tumor nuclear membranes mediated by superoxide radicals].[超氧自由基介导的肿瘤核膜对肾上腺素的氧化作用]
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Generation of free radicals of quinone group-containing anti-cancer chemicals in NADPH-microsome system as evidenced by initiation of sulfite oxidation.通过亚硫酸盐氧化的引发证明含醌基抗癌化学物质在NADPH-微粒体系统中产生自由基。
Gan. 1975 Feb;66(1):43-7.
8
Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers.蒽环类抗癌药物对小鼠心脏和肝脏微粒体脂质过氧化的刺激作用：活性氧清除剂的特性及影响
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9
Enhancement of DNA chain breakage by bleomycin A2 in the presence of microsomes and reduced nicotinamide adenine dinucleotide phosphate.
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Daunorubicin metabolism by rat tissue preparations.
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HSP90 inhibitor 17-DMAG exerts anticancer effects against gastric cancer cells principally by altering oxidant-antioxidant balance.热休克蛋白90抑制剂17-二甲基澳瑞他汀E主要通过改变氧化还原平衡发挥对胃癌细胞的抗癌作用。
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