Isham V
Department of Statistical Science, University College London, U.K.
Philos Trans R Soc Lond B Biol Sci. 1989 Sep 5;325(1226):113-21. doi: 10.1098/rstb.1989.0076.
The aim of the method of 'back projection' is to provide estimates of the number of new infections with the human immunodeficiency virus (HIV) as a function of time, by using the numbers of diagnoses of the acquired immune deficiency syndrome (AIDS) together with information on the distribution of the incubation period between infection and diagnosis. Here, the method is investigated with particular reference to cases of HIV infection and AIDS in the United Kingdom.
“反向推算”方法的目的是,通过利用获得性免疫缺陷综合征(艾滋病)的诊断数量以及感染与诊断之间潜伏期分布的信息,来提供作为时间函数的人类免疫缺陷病毒(HIV)新感染人数的估计值。在此,特别针对英国的HIV感染和艾滋病病例对该方法进行研究。