Booth T F
Natural Environment Research Council Institute of Virology, Oxford, Great Britain.
Exp Appl Acarol. 1989 Sep;7(4):259-66. doi: 10.1007/BF01197920.
Oviposition in the cattle tick Boophilus microplus was arrested by octopamine and the alpha-adrenergic agonists clonidine, tolazoline, and naphazoline, at doses of 25 micrograms per tick. The same effect was obtained with a sublethal dose of Amitraz of 10 micrograms per tick. In contrast, the alpha-adrenergic agonists apomorphine, synephrine, phentolamine, metaclopromide and chlorpromazine were ineffective. No mortality was observed at any of the doses tested. Reserpine, which depletes endogenous adrenergic terminals, mimicked the effects of octopamine in blocking oviposition. Acetylcholine agonists also blocked oviposition but dopaminergic agonists did not. Evidence is presented suggesting that control of the oviduct is mediated by octopaminergic receptors.
用章鱼胺以及α - 肾上腺素能激动剂可乐定、妥拉唑啉和萘甲唑啉，以每只蜱25微克的剂量处理微小牛蜱时，其产卵受到抑制。用每只蜱10微克的亚致死剂量双甲脒也可获得相同效果。相比之下，α - 肾上腺素能激动剂阿扑吗啡、辛弗林、酚妥拉明、甲氧氯普胺和氯丙嗪则无效。在所测试的任何剂量下均未观察到死亡情况。利血平可耗尽内源性肾上腺素能终末，它在阻断产卵方面模拟了章鱼胺的作用。乙酰胆碱激动剂也能阻断产卵，但多巴胺能激动剂则不能。有证据表明，输卵管的控制是由章鱼胺能受体介导的。
