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儿童非酒精性脂肪性肝病

Non-alcoholic Fatty liver disease in children.

作者信息

Singer Cristina, Stancu Polixenia, Coşoveanu Simona, Botu Alina

机构信息

University of Medicine and Pharmacy of Craiova, 2nd Pediatric Clinic, Emergency County Hospital Craiova, Romania.

出版信息

Curr Health Sci J. 2014 Jul-Sep;40(3):170-6. doi: 10.12865/CHSJ.40.03.03. Epub 2014 Aug 4.

Abstract

In the last years, there has been extremely much information which reveals an alarming increase of obesity in children and, at the same time, an increase of the incidence of non-alcoholic fatty liver disease (NAFLD). NAFLD implies a wide range of affections starting from simple hepatic steatosis to non-alcoholic steatohepatitis (NASH); the latter can evolve to cirrhosis and hepatic carcinoma. All these affections were noticed in children, too. The article presents data on the epidemiology, pathogeny, clinical and paraclinical findings, and treatment of NAFLD in children.

摘要

在过去几年中,有大量信息表明儿童肥胖现象急剧增加,与此同时,非酒精性脂肪性肝病(NAFLD)的发病率也在上升。NAFLD涵盖了从单纯性肝脂肪变性到非酒精性脂肪性肝炎(NASH)等一系列病症;后者可能发展为肝硬化和肝癌。所有这些病症在儿童中也有发现。本文介绍了儿童NAFLD的流行病学、发病机制、临床和辅助检查结果以及治疗方面的数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f896/4340436/772d165b6475/CHSJ-40-3-170-fig1.jpg

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