Denters Maaike J, Bossuyt Patrick M, Deutekom Marije, Fockens Paul, Dekker Evelien
Departments of aGastroenterology and Hepatology bBiostatistics and Clinical Epidemiology cSocial Medicine, Academic Medical Centre, Amsterdam, The Netherlands.
Eur J Cancer Prev. 2015 May;24(3):176-9. doi: 10.1097/CEJ.0000000000000139.
Several clinical trials have shown that colorectal cancer (CRC) screening can reduce cancer deaths. Its effectiveness is affected by the participation level. To develop targeted invitations, we need to understand why individual persons decide to participate. To evaluate reasons for participation among persons invited for faecal immunochemical test-based CRC screening, a total of 10,265 asymptomatic persons aged 50-75 years were invited to a Dutch CRC screening pilot (2008-2009). Reasons for participation were elicited by a questionnaire. A total of 3554 (66%) participants returned the questionnaire. Obtaining more certainty about the chances of developing cancer (ticked by 88%) and the occurrence of cancer in the family or the circle of acquaintances (18%) were the most frequently selected reasons for participation. We also explored reasons for nonparticipation among nonparticipants. In this subgroup, comorbidity and the absence of symptoms were the most frequently reported reasons for declining to participate, but the response rate was low. The vast majority of the participants decided to take up the screening because they wanted to know more about their chances of developing cancer.
多项临床试验表明，结直肠癌（CRC）筛查可降低癌症死亡率。其有效性受参与程度的影响。为制定有针对性的邀请，我们需要了解个人决定参与的原因。为评估基于粪便免疫化学检测的CRC筛查受邀者的参与原因，共有10265名年龄在50至75岁之间的无症状者受邀参加一项荷兰CRC筛查试点项目（2008 - 2009年）。参与原因通过问卷调查得出。共有3554名（66%）参与者返回了问卷。对患癌几率获得更多确定性（88%勾选）以及家族或熟人圈子中有癌症发生（18%）是最常被选择的参与原因。我们还探究了未参与者不参与的原因。在这个亚组中，合并症和无症状是最常被报告的拒绝参与的原因，但回复率较低。绝大多数参与者决定接受筛查是因为他们想更多地了解自己患癌的几率。
