Perez-Alamino Rodolfo, Maldonado-Ficco Hernán
Rheumatology Section, Hospital Nicolás Avellaneda, 2000 Catamarca Street, Tucumán, Argentina,
Curr Rheumatol Rep. 2015 Mar;17(3):12. doi: 10.1007/s11926-015-0497-0.
The systemic vasculitis is a heterogeneous group of diseases characterized by the inflammation of blood vessels. The development of advanced diagnostic tests and genetic studies have resulted in greater improvement in our understanding of vasculitis pathogenesis and thus in the development of newer therapies. However, there is still an unmet need in the management of systemic vasculitis, focused on developing of new biomarkers that would enable distinction between active disease from damage or infection and predict treatment response and prognosis.
系统性血管炎是一组异质性疾病，其特征为血管炎症。先进诊断测试和基因研究的发展使我们对血管炎发病机制的理解有了更大的进步，从而推动了新疗法的开发。然而，在系统性血管炎的管理方面仍存在未满足的需求，重点在于开发新的生物标志物，以区分活动性疾病与损伤或感染，并预测治疗反应和预后。
