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从褐藻羊栖菜中提取的多糖的免疫调节活性。

Immune-modulating activities of polysaccharides extracted from brown algae Hizikia fusiforme.

作者信息

Jeong Sang Chul, Jeong Yong Tae, Lee Sang Myung, Kim Jin Hee

机构信息

a HK Bio, Business Incubator , Daegu Haany University , Gyeongsan , Republic Korea.

出版信息

Biosci Biotechnol Biochem. 2015;79(8):1362-5. doi: 10.1080/09168451.2015.1018121. Epub 2015 Mar 6.

DOI:10.1080/09168451.2015.1018121
PMID:25744337
Abstract

The immuno-modulating activities of seaweed (Hizikia fusiforme) extracts on murine macrophage and splenocyte were studied in vitro. Polysaccharide (HFP) exhibited the potential macrophage stimulating effects than water extract (HFW) such as NO production and enhanced pro-inflammatory cytokines on the Raw 264.7 cells and splenocytes. From the mono-sugar composition, HFP-associated fucose based on HFP of H. fusiforme acts as immune modulator.

摘要

体外研究了海藻（羊栖菜）提取物对小鼠巨噬细胞和脾细胞的免疫调节活性。多糖（HFP）比水提取物（HFW）表现出更强的巨噬细胞刺激作用，如在Raw 264.7细胞和脾细胞上产生一氧化氮以及增强促炎细胞因子。从单糖组成来看，基于羊栖菜HFP的岩藻糖基化HFP作为免疫调节剂发挥作用。

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