Bussy Frederick, Matthieu Le Goff, Salmon Henri, Delaval José, Berri Mustapha, Pi Nyvall Collén
Amadéite, ZA du Haut du Bois, 56580 Bréhan, France.
INRA, Université Tours, 37380 Nouzilly, France.
Vet Anim Sci. 2019 Feb 10;7:100051. doi: 10.1016/j.vas.2019.100051. eCollection 2019 Jun.
The transfer of passive immunity from sows to piglets can be improved through the administration of immuno-stimulating products before farrowing. This study evaluated the immuno-stimulating effect of an algal sulfated polysaccharide extract (MSP extract) from the green algae when administrated orally to sows at the end of gestation. Four diets were tested: Control (no MSP extract), MSP1 (2 g/day of MSP extract), MSP2 (8 g/day), and MSP3 (16 g/day). The experimental diets were provided in two periods: before the last atrophic rhinitis vaccine booster, and a week before farrowing. Anti- IgG antibodies were recorded in blood, colostrum, and milk, and total IgA were measured in colostrum and milk. Titer kinetics between the blood sampled before farrowing and colostrum displayed an increase in specific IgG for MSP3. Moreover, the MSP2 diet increased the level of total IgA in milk compared to the control group. Although the immuno-stimulating effect of MSP extract on piglet performance was not concurrent across the different supplementation levels, the present study supports the use of natural algae extract (MSP) as an immunomodulating solution in swine production.
在分娩前给予免疫刺激产品，可以提高母猪向仔猪传递被动免疫力的能力。本研究评估了在妊娠末期给母猪口服一种从绿藻中提取的藻硫酸化多糖提取物（MSP提取物）的免疫刺激效果。测试了四种日粮：对照组（无MSP提取物）、MSP1组（2克/天的MSP提取物）、MSP2组（8克/天）和MSP3组（16克/天）。实验日粮分两个阶段提供：在最后一次萎缩性鼻炎疫苗加强免疫前，以及分娩前一周。记录血液、初乳和乳汁中的抗IgG抗体，并测量初乳和乳汁中的总IgA。分娩前采集的血液与初乳之间的滴度动力学显示，MSP3组的特异性IgG有所增加。此外，与对照组相比，MSP2日粮增加了乳汁中总IgA的水平。尽管MSP提取物对仔猪性能的免疫刺激作用在不同补充水平上并非同时出现，但本研究支持将天然藻类提取物（MSP）用作猪生产中的免疫调节解决方案。
