Abuhandan Mahmut, Solmaz Abdullah, Geter Suleyman, Kaya Cemil, Guzel Bulent, Yetkin Ilhan, Koca Bulent
Department of Pediatrics, Medical Faculty, Harran University, Sanliurfa, Turkey.
Iran J Pediatr. 2014 Aug;24(4):401-5. Epub 2014 Jul 2.
This study aimed to evaluate serum selenium levels and mean platelet volume in children who experience simple febrile convulsion.
The study comprised 42 patients diagnosed with simple febrile convulsions and a control group of 30 healthy children. Blood samples were taken following a febrile convulsion. Selenium levels in the serum of both the patients and control subjects were measured with the hydride formation method on an atomic absorption spectrometry device and mean platelet volume was evaluated.
When the mean values of the febrile convulsion patients were compared with those of the control group, the mean selenium levels and thrombocyte count were found to be statistically significantly low (P=0.002, P=0.01 respectively) and the mean platelet volume values were statistically significantly high (P=0.002).
While low serum selenium levels cause the onset of a febrile seizure in patients with simple febrile convulsion, it is thought that the increased mean platelet volume shows infection activity causing febrile convulsion.
本研究旨在评估单纯性热性惊厥患儿的血清硒水平和平均血小板体积。
该研究包括42例被诊断为单纯性热性惊厥的患者和30名健康儿童组成的对照组。在热性惊厥发作后采集血样。采用氢化物发生法在原子吸收光谱仪上测量患者和对照受试者血清中的硒水平，并评估平均血小板体积。
将热性惊厥患者的平均值与对照组进行比较时，发现平均硒水平和血小板计数在统计学上显著降低（分别为P = 0.002，P = 0.01），而平均血小板体积值在统计学上显著升高（P = 0.002）。
虽然血清硒水平低会导致单纯性热性惊厥患者发生热性惊厥，但认为平均血小板体积增加表明存在导致热性惊厥的感染活动。
