热性惊厥患儿体内主要和微量元素状况

Major and minor bio-element status in children with febrile seizure.

作者信息

Akbayram S, Cemek M, Büyükben A, Aymelek F, Karaman S, Yilmaz F, Dogan M, Caksen H

机构信息

Department of Pediatrics, Yuzuncu Yil University, Van, Turkey.

出版信息

Bratisl Lek Listy. 2012;113(7):421-3. doi: 10.4149/bll_2012_095.

DOI:10.4149/bll_2012_095

PMID:22794517

Abstract

Febrile seizures (FS) are the most common cause of seizures in children. The exact etiopathogenesis is unknown but involves factors like genetic predisposition and alterations in the levels of neurotransmitters and some trace elements. The study includes 48 consecutive children with FS, and 55 healthy age matched control subjects. Calcium, magnesium and potassium concentrations in the febrile study group were lower than in the control group (p<0.05). Iron and Gallium levels in the study group were lower than in the control group (p<0.01). Serum Selenium (p<0.001), Zinc (p<0.001) and Strontium (p0.05). The aim of the present prospective analytical case-control study was to determine whether there was any change in element levels in children with FS (Ref. 33).

摘要

热性惊厥（FS）是儿童惊厥最常见的病因。确切的发病机制尚不清楚，但涉及遗传易感性、神经递质水平改变和一些微量元素等因素。该研究纳入了48例连续的FS患儿以及55例年龄匹配的健康对照者。热性研究组的钙、镁和钾浓度低于对照组（p<0.05）。研究组的铁和镓水平低于对照组（p<0.01）。血清硒（p<0.001）、锌（p<0.001）和锶（p0.05）。本前瞻性分析病例对照研究的目的是确定FS患儿的元素水平是否有任何变化（参考文献33）。