裂褶菌引起的变应性真菌性鼻鼻窦炎及鼻窦支气管真菌病。

Tsukatani Toshiaki, Ogawa Haruhiko, Anzawa Kazushi, Kobayashi Eiji, Hasegawa Hiroki, Makimura Koichi, Yoshizaki Tomokazu, Ueda Norishi

Department of Otorhinolaryngology, Public Central Hospital of Matto Ishikawa, Hakusan, Ishikawa 924-8588, Japan.

Division of Pulmonary Medicine, Ishikawa-ken Saiseikai Kanazawa Hospital, Kanazawa, Ishikawa, Japan.

Med Mycol Case Rep. 2015 Feb 24;8:10-3. doi: 10.1016/j.mmcr.2015.02.004. eCollection 2015 Jun.

We present 32- and 38-year-old males with Schizophyllum commune-induced allergic fungal rhinosinusitis (AFRS). S. commune-induced AFRS was diagnosed by clinical and radiographic findings, positive specific IgE antibodies against S. commune as measured by the ImmunoCAP system, and sequencing analysis of the fungus. Our two cases with S. commune-induced AFRS for the first time showed evidence for type 1 hypersensitivity to S. commune as determined by using specific IgE antibodies against S. commune, and the fungus was identified by sequence analysis.

我们报告了两例分别为32岁和38岁男性的由裂褶菌引起的变应性真菌性鼻-鼻窦炎（AFRS）。通过临床和影像学检查结果、免疫CAP系统检测出的针对裂褶菌的特异性IgE抗体阳性以及对该真菌的测序分析，确诊为裂褶菌引起的AFRS。我们这两例由裂褶菌引起的AFRS首次通过使用针对裂褶菌的特异性IgE抗体确定了对裂褶菌的1型超敏反应证据，并通过序列分析鉴定了该真菌。