一例由裂殖菌引起的变应性真菌性鼻鼻窦炎，该菌同时存在于患者的鼻腔痰和门廊土壤样本中。

A case of allergic fungal rhinosinusitis caused by Schizophyllum commune identified in both patient's nasal sputum and veranda's soil samples.

机构信息

Department of Health Care, Fukujuji Hospital, Japan Anti-Tuberculosis Association, 3-1-24 Matsuyama, Kiyose, Tokyo, Japan.

Department of Clinical Laboratory, Fukujuji Hospital, Japan Anti-Tuberculosis Association, 3-1-24 Matsuyama, Kiyose, Tokyo, Japan.

出版信息

J Infect Chemother. 2021 May;27(5):759-765. doi: 10.1016/j.jiac.2020.12.015. Epub 2020 Dec 30.

DOI:10.1016/j.jiac.2020.12.015

PMID:33388231

Abstract

This is a case report of allergic fungal rhinosinusitis caused by Schizophyllum commune (S. commune) identified in a patient's nasal mucus and environmental soil sample using (r)DNA sequencing. Although filamentous basidiomycetes, including S. commune, are known as environmental pathogens causing allergic respiratory diseases worldwide, many patients with infections caused by S. commune have not been correctly diagnosed. Repeated exposures to environmental floating fungi supposedly make an easy sensitization and colonization of fungi in the nasal passages, resulting in the onset of allergic fungal rhinosinusitis due to S. commune in our living environments. This report indicates the importance of reconsidering allergic respiratory diseases associated with our living environments.

摘要

这是一例由裂褶菌（Schizophyllum commune，S. commune）引起的变应性真菌性鼻鼻窦炎的病例报告，通过（r）DNA 测序从患者的鼻腔黏液和环境土壤样本中鉴定出该菌。尽管包括裂褶菌在内的丝状担子菌被认为是引起全球变应性呼吸道疾病的环境病原体，但许多由裂褶菌引起感染的患者并未得到正确诊断。据推测，反复暴露于环境漂浮真菌中会使真菌容易在鼻腔中致敏和定植，从而导致我们生活环境中的裂褶菌引起的变应性真菌性鼻鼻窦炎的发生。本报告表明需要重新考虑与我们生活环境相关的变应性呼吸道疾病。