通过光谱域光学相干断层扫描（SD-OCT）在HLA-B27阳性前葡萄膜炎中检测到的亚临床黄斑水肿。
Subclinical Macular Edema Detected by Spectral-domain Optical Coherence Tomography (SD-OCT) in HLA-B27 Positive Anterior Uveitis.
作者信息
Moschos Marilita M
机构信息
Department of Ophthalmology, University of Athens, Greece.
出版信息
Med Hypothesis Discov Innov Ophthalmol. 2014 Winter;3(4):123-6.
PURPOSE
To assess foveal thickness by spectral-domain optical coherence tomography (SD-OCT) during acute anterior uveitis (AAU) in HLA-B27 patients.
METHODS
Foveal thickness was measured at baseline and after clinical resolution of the uveitis. Data of the affected eyes of 11 patients were compared to those of a fellow, healthy eyes and to those of counterpart volunteers.
RESULTS
At baseline mean foveal thickness was 190 ± 28 µm in affected eyes, 166 ± 20 µm in fellow eyes (p < 0.001), and 162±14 µm in control group (p = 0.01). On the second OCT evaluation, no significant change was observed in affected eyes while the difference versus fellow eyes and control group remained statistically significant.
CONCLUSIONS
A significant increase in foveal thickness was observed in eyes with HLA -B27 AAU when compared with healthy eyes. The difference persisted for at least one month, despite full clinical and functional recovery.
目的
通过光谱域光学相干断层扫描（SD-OCT）评估HLA-B27患者急性前葡萄膜炎（AAU）期间的黄斑厚度。
方法
在基线时以及葡萄膜炎临床消退后测量黄斑厚度。将11例患者患眼的数据与对侧健康眼以及对应志愿者的数据进行比较。
结果
基线时，患眼的平均黄斑厚度为190±28µm，对侧眼为166±20µm（p<0.001），对照组为162±14µm（p=0.01）。在第二次OCT评估时，患眼中未观察到显著变化，但其与对侧眼和对照组之间的差异仍具有统计学意义。
结论
与健康眼相比，HLA-B27 AAU患者的患眼黄斑厚度显著增加。尽管临床和功能已完全恢复，但这种差异至少持续了一个月。
Zotero 插件