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在成年1型糖尿病患者中,健康的生活方式与更好的心脏代谢状况相关。

In adult patients with type 1 diabetes healthy lifestyle associates with a better cardiometabolic profile.

作者信息

Leroux C, Gingras V, Desjardins K, Brazeau A-S, Ott-Braschi S, Strychar I, Rabasa-Lhoret R

机构信息

Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Quebec, Canada; Department of Nutrition, Université de Montréal, Montreal, Quebec, Canada.

Institut de Recherches Cliniques de Montréal (IRCM), Montreal, Quebec, Canada.

出版信息

Nutr Metab Cardiovasc Dis. 2015 May;25(5):444-51. doi: 10.1016/j.numecd.2015.01.004. Epub 2015 Jan 28.

Abstract

BACKGROUND/AIMS: Little is known about lifestyle habits of adults with type 1 diabetes (T1D) and their association with cardiometabolic risk (CMR) factors. The aims of the present study were to determine the prevalence of adults with T1D who adopted a healthy lifestyle and to explore the association between a healthy lifestyle and the cardiometabolic profile.

METHODS AND RESULTS

This is a cross-sectional analysis of 115 adults with T1D. Participants wore a motion sensor and completed a 3-day food record. The following CMR factors were assessed: body mass index, waist circumference, body composition (iDXA), glycated hemoglobin, lipids and blood pressure. Insulin resistance was estimated (estimated glucose disposal rate). Participants were classified according to the number of healthy lifestyle habits adopted (ranging from 0 to 3): regular physical activity (physical activity level ≥1.7), good diet quality (Canadian Healthy Eating Index score >80) and none-smoking status. The proportion of participants who adopted 3, 2, 1 or 0 lifestyle habits were 11%, 30%, 37%, and 23%, respectively. As the number of healthy lifestyle habits adopted increased, participants had significantly lower body mass index, waist circumference, body fat, total cholesterol, non-HDL-cholesterol, triglycerides and systolic blood pressure (p < 0.05). In addition, a trend for lower estimated insulin resistance was observed (p = 0.06). For each increase of one healthy lifestyle habit, body mass index decreased by 1.9 kg/m(2), waist circumference by 4.0 cm for men and 4.8 cm for women and trunk fat by 3.6% for men and 4.1% for women.

CONCLUSIONS

These results suggest the importance of a healthy lifestyle among adults with T1D in order to control CMR factors.

摘要

背景/目的:关于1型糖尿病(T1D)成人的生活方式习惯及其与心脏代谢风险(CMR)因素的关联,我们所知甚少。本研究的目的是确定采用健康生活方式的T1D成人的患病率,并探讨健康生活方式与心脏代谢状况之间的关联。

方法与结果

这是一项对115名T1D成人的横断面分析。参与者佩戴运动传感器并完成3天的饮食记录。评估了以下CMR因素:体重指数、腰围、身体成分(双能X线吸收法)、糖化血红蛋白、血脂和血压。估算胰岛素抵抗(估算葡萄糖处置率)。根据采用的健康生活方式习惯数量(范围为0至3)对参与者进行分类:规律体育活动(身体活动水平≥1.7)、良好饮食质量(加拿大健康饮食指数得分>80)和非吸烟状态。采用3种、2种、1种或0种生活方式习惯的参与者比例分别为11%、30%、37%和23%。随着采用的健康生活方式习惯数量增加,参与者的体重指数、腰围、体脂、总胆固醇、非高密度脂蛋白胆固醇、甘油三酯和收缩压显著降低(p<0.05)。此外,观察到估算胰岛素抵抗有降低趋势(p=0.06)。每增加一种健康生活方式习惯,体重指数降低1.9kg/m²,男性腰围降低4.0cm,女性降低4.8cm,男性躯干脂肪降低3.6%,女性降低4.1%。

结论

这些结果表明健康生活方式对T1D成人控制CMR因素的重要性。

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