Kumar Surendra, Ghosh Subhojit, Tetarway Suhash, Sinha Rakesh Kumar
Department of Bio-Engineering, Birla Institute of Technology, Mesra, Ranchi, 835215, Jharkhand, India,
Med Biol Eng Comput. 2015 Jul;53(7):609-22. doi: 10.1007/s11517-015-1264-0. Epub 2015 Mar 13.
In this study, the magnitude and spatial distribution of frequency spectrum in the resting electroencephalogram (EEG) were examined to address the problem of detecting alcoholism in the cerebral motor cortex. The EEG signals were recorded from chronic alcoholic conditions (n = 20) and the control group (n = 20). Data were taken from motor cortex region and divided into five sub-bands (delta, theta, alpha, beta-1 and beta-2). Three methodologies were adopted for feature extraction: (1) absolute power, (2) relative power and (3) peak power frequency. The dimension of the extracted features is reduced by linear discrimination analysis and classified by support vector machine (SVM) and fuzzy C-mean clustering. The maximum classification accuracy (88 %) with SVM clustering was achieved with the EEG spectral features with absolute power frequency on F4 channel. Among the bands, relatively higher classification accuracy was found over theta band and beta-2 band in most of the channels when computed with the EEG features of relative power. Electrodes wise CZ, C3 and P4 were having more alteration. Considering the good classification accuracy obtained by SVM with relative band power features in most of the EEG channels of motor cortex, it can be suggested that the noninvasive automated online diagnostic system for the chronic alcoholic condition can be developed with the help of EEG signals.
在本研究中,对静息脑电图(EEG)频谱的幅度和空间分布进行了检测,以解决大脑运动皮层中酒精中毒的检测问题。EEG信号记录于慢性酒精中毒患者(n = 20)和对照组(n = 20)。数据取自运动皮层区域,并分为五个子带(δ、θ、α、β-1和β-2)。采用了三种特征提取方法:(1)绝对功率,(2)相对功率,(3)峰值功率频率。通过线性判别分析降低提取特征的维度,并通过支持向量机(SVM)和模糊C均值聚类进行分类。使用F4通道上具有绝对功率频率的EEG频谱特征,SVM聚类实现了最高分类准确率(88%)。在各频段中,当使用相对功率的EEG特征进行计算时,大多数通道在θ频段和β-2频段的分类准确率相对较高。电极方面,CZ、C3和P4的变化更大。考虑到SVM在运动皮层的大多数EEG通道中使用相对频段功率特征获得了良好的分类准确率,因此可以建议借助EEG信号开发慢性酒精中毒状况的非侵入性自动在线诊断系统。