Agrawal Rupesh, Bhan Kanchan, Balaggan Kam, Lee Richard Wj, Pavesio Carlos E, Addison Peter Kf
Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK ; Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, 162 City Road, London, EC1V 2PD UK ; National Healthcare Group Eye Institute, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433 Singapore.
Moorfields Eye Hospital, NHS Foundation Trust, 162 City Road, London, EC1V 2PD UK.
J Ophthalmic Inflamm Infect. 2015 Feb 1;5:2. doi: 10.1186/s12348-015-0034-3. eCollection 2015.
Acute maculopathy is a rare condition of unknown aetiology and Coxsackie virus is known to be associated with this macular chorioretinitis.
We report a case of acute unilateral maculopathy in a 35-year-old woman with concurrent hand foot and mouth disease. Furthermore, we display multimodal imaging (colour fundus photographs, autofluorescence, spectral domain ocular coherence tomography, fluorescein angiography and indocyanine green angiography) charting the course of the disease. The source of the virus was thought to be the patient's child. Empirical treatment with oral corticosteroids was commenced and the inflammation resolved, leaving a residual macular scar.
We present this case combined with the review of literature of adult onset Coxsackie-virus-associated retinitis. This case reiterates the fact that Coxsackie virus is an uncommon but important consideration in the differential diagnosis of chorioretinitis and posterior uveitis with atypical retinopathy.
急性黄斑病变是一种病因不明的罕见病症,已知柯萨奇病毒与这种黄斑脉络膜视网膜炎有关。
我们报告了一例35岁患有手足口病的女性急性单侧黄斑病变病例。此外,我们展示了多模态成像(彩色眼底照片、自发荧光、频域光学相干断层扫描、荧光素血管造影和吲哚菁绿血管造影)来记录疾病的发展过程。病毒来源被认为是患者的孩子。开始使用口服皮质类固醇进行经验性治疗,炎症消退,留下黄斑残余瘢痕。
我们结合成人柯萨奇病毒相关性视网膜炎的文献回顾呈现此病例。该病例重申了一个事实,即柯萨奇病毒在脉络膜视网膜炎和伴有非典型视网膜病变的后葡萄膜炎的鉴别诊断中虽不常见但却是重要的考虑因素。