Liu Hongting, Bittencourt Millena G, Sophie Raafay, Sepah Yasir J, Hanout Mostafa, Rentiya Zubir, Annam Rachel, Scholl Hendrik P N, Nguyen Quan Dong
Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA ; Visual Science and Optometry Center, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi Province, China.
Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA.
Transl Vis Sci Technol. 2015 Mar 10;4(2):3. doi: 10.1167/tvst.4.2.3. eCollection 2015 Mar.
We compared the fixation stability measurements obtained with two microperimeters, the Micro Perimeter 1 (MP-1) and the Spectral OCT/SLO (OCT/SLO), in subjects with and without maculopathies.
A total of 41 eyes with no known ocular diseases and 45 eyes with maculopathies were enrolled in the study. Both eyes of each participant had a 20-second fixation test using the MP-1 and OCT/SLO. The bivariate contour ellipse area (BCEA) was used for fixation stability evaluation.
In the normal group, BCEA was 2.93 ± 0.32 log minarc on OCT/SLO and 2.89 ± 0.30 log minarc on MP-1. In the maculopathy group, BCEA was 3.05 ± 0.41 log minarc on OCT/SLO and 3.15 ± 0.46 log minarc on MP-1. There was no statistically significant difference between the BCEA measured by OCT/SLO and by MP-1 in both groups. A moderate correlation was found between the two devices ( = 0.45, < 0.001). The sample size during the fixation test was 535.5 ± 14.6 pairs of coordinates in the normal group and 530.7 ± 14.9 pairs in the maculopathy group with MP-1, while it was 72.3 ± 6.9 and 59.9 ± 10.1, respectively, with OCT/SLO. This was due to different tracking frequencies between the two microperimeters.
Fixation stability assessment yields similar results using the OCT/SLO and MP-1. A major difference in sampling rate between the two microperimeters does not significantly affect BCEA measurements.
Fixation stability assessments are comparable and interchangeable between the OCT/SLO and the MP-1.
我们比较了在患有和未患有黄斑病变的受试者中,使用两种微视野计(微视野计1(MP-1)和光谱光学相干断层扫描/扫描激光检眼镜(OCT/SLO))获得的注视稳定性测量结果。
共有41只无已知眼部疾病的眼睛和45只患有黄斑病变的眼睛纳入本研究。每位参与者的双眼均使用MP-1和OCT/SLO进行了20秒的注视测试。使用双变量轮廓椭圆面积(BCEA)评估注视稳定性。
在正常组中,OCT/SLO上的BCEA为2.93±0.32对数分钟弧度,MP-1上为2.89±0.30对数分钟弧度。在黄斑病变组中,OCT/SLO上的BCEA为3.05±0.41对数分钟弧度,MP-1上为3.15±0.46对数分钟弧度。两组中OCT/SLO和MP-1测量的BCEA之间无统计学显著差异。两种设备之间发现中度相关性(=0.45,<0.001)。使用MP-1时,正常组注视测试期间的样本量为535.5±14.6对坐标,黄斑病变组为530.7±14.9对;而使用OCT/SLO时,分别为72.3±6.9和59.9±10.1。这是由于两种微视野计的跟踪频率不同。
使用OCT/SLO和MP-1进行注视稳定性评估产生相似的结果。两种微视野计采样率的主要差异不会显著影响BCEA测量。
OCT/SLO和MP-1之间的注视稳定性评估具有可比性且可互换。