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大规模分发运动后单次或重复家访对杀虫剂处理蚊帐悬挂和使用的影响——一项整群随机对照试验

The effect of single or repeated home visits on the hanging and use of insecticide-treated mosquito nets following a mass distribution campaign--a cluster randomized, controlled trial.

作者信息

Kilian Albert, Balayo Connie, Feldman Mitra, Koenker Hannah, Lokko Kojo, Ashton Ruth A, Bruce Jane, Lynch Matthew, Boulay Marc

机构信息

Malaria Consortium, London, United Kingdom; Tropical Health LLP, Montagut, Spain.

Malaria Control Program, Ministry of Health, Kampala, Uganda.

出版信息

PLoS One. 2015 Mar 16;10(3):e0119078. doi: 10.1371/journal.pone.0119078. eCollection 2015.

Abstract

BACKGROUND

Study objective was to evaluate the effectiveness of commonly used post-campaign hang-up visits on the hanging and use of campaign nets.

METHODS

A cluster-randomized trial was carried out in Uganda following an ITN distribution campaign. Five clusters (parishes, consisting of ∼11 villages each) were randomly selected for each of the three study arms with between 7,534 and 9,401 households per arm. Arm 1 received one hang-up visit, while Arm 2 received two visits by volunteers four and seven months after the campaign. Visits consisted of assistance hanging the net and education on net use. The control arm was only exposed to messages during the campaign itself. Three cross-sectional surveys with a two-stage cluster sampling design, representative of the study populations, were carried out to capture the two key outcome variables of net hanging and ITN use. Sample size was calculated to detect at least a 15 percentage-points change in net use, and was 1811 at endline. The analysis used an intention-to-treat approach.

FINDINGS

Both hanging and use of ITN increased during follow-up in a similar way in all three study arms. The proportion of the population using an ITN the previous night was 64.0% (95% CI 60.8, 67.2), for one additional visit, 68.2% (63.8, 72.2) for two visits and 64.0% (59.4, 68.5) for the control. The proportion of households with all campaign nets hanging increased from 55.7% to 72.5% at endline (p<0.0005 for trend), with no difference between study arms. Financial cost per household visited was estimated as USD 2.33 for the first visit and USD 2.24 for the second.

CONCLUSIONS

Behavior change communication provided during the campaign or through other channels was sufficient to induce high levels of net hanging and use and additional "hang-up" activities were not cost-effective.

摘要

背景

研究目的是评估常用的活动后上门回访对蚊帐悬挂及使用情况的有效性。

方法

在乌干达开展一项蚊帐分发活动后进行了一项整群随机试验。三个研究组每组随机选取五个整群(教区,每个教区由约11个村庄组成),每组有7534至9401户家庭。第一组接受一次上门回访,第二组在活动后四个月和七个月由志愿者进行两次回访。回访包括协助悬挂蚊帐以及蚊帐使用教育。对照组仅在活动期间接触相关信息。采用两阶段整群抽样设计进行了三次横断面调查,以代表研究人群,旨在获取蚊帐悬挂和驱虫蚊帐使用这两个关键结局变量。计算样本量以检测蚊帐使用至少15个百分点的变化,最终样本量为1811。分析采用意向性分析方法。

结果

在所有三个研究组中,随访期间驱虫蚊帐的悬挂和使用均以类似方式增加。前一晚使用驱虫蚊帐的人群比例,第一组为64.0%(95%置信区间60.8, 67.2),额外回访一次的第二组为68.2%(63.8, 72.2),两次回访的第二组为68.2%(63.8, 72.2),对照组为64.0%(59.4, 68.5)。到随访结束时,所有活动发放蚊帐均已悬挂的家庭比例从55.7%增至72.5%(趋势p<0.0005),各研究组之间无差异。每次上门回访的每户财务成本估计第一次为2.33美元,第二次为2.24美元。

结论

活动期间或通过其他渠道提供的行为改变沟通足以促使高水平的蚊帐悬挂和使用,额外的“上门回访”活动不具有成本效益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d150/4361725/26177bdd9932/pone.0119078.g001.jpg

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