Kendler K S, Aggen S H, Li Y, Lewis C M, Breen G, Boomsma D I, Bot M, Penninx B W J H, Flint J
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University,Richmond,VA,USA.
Wellcome Trust Centre for Human Genetics,Oxford,UK.
Psychol Med. 2015 Jul;45(9):1945-54. doi: 10.1017/S0033291714003067. Epub 2015 Mar 17.
Do DSM-IV diagnostic criteria for major depression (MD) in Chinese and Western women perform in a similar manner?
The CONVERGE study included interview-based assessments of women of Han Chinese descent with treated recurrent MD. Using Mplus software, we investigated the overall degree of between-sample measurement invariance (MI) for DSM-IV diagnostic criteria for MD in the CONVERGE sample and samples selected from four major Western studies from the USA and Europe matched to the inclusion criteria of CONVERGE. These analyses were performed one pair at a time. We then compared the results from CONVERGE paired with Western samples to those obtained when examining levels of MI between pairs of the Western samples.
Assuming a single factor model for the nine diagnostic criteria for MD, the level of MI based on global fit indexes observed between the CONVERGE and the four Western samples was very similar to that seen between the Western samples. Comparable results were obtained when using a two-factor structure for MI testing when applied to the 14 diagnostic criteria for MD disaggregated for weight, appetite, sleep, and psychomotor changes.
Despite differences in language, ethnicity and culture, DSM criteria for MD perform similarly in Chinese women with recurrent MD and comparable subjects from the USA and Europe. The DSM criteria for MD may assess depressive symptoms that are relatively insensitive to cultural and ethnic differences. These results support efforts to compare findings from depressed patients in China and Western countries.
中国和西方女性中,《精神疾病诊断与统计手册》第四版(DSM-IV)中重度抑郁症(MD)的诊断标准表现是否相似?
CONVERGE研究纳入了对患有复发性MD且接受治疗的汉族女性的访谈式评估。我们使用Mplus软件,调查了CONVERGE样本以及从美国和欧洲四项主要西方研究中选取的符合CONVERGE纳入标准的样本中,MD的DSM-IV诊断标准的样本间测量不变性(MI)的总体程度。这些分析每次对一对样本进行。然后,我们将CONVERGE与西方样本配对的结果,与检查西方样本对之间MI水平时获得的结果进行比较。
假设MD的九项诊断标准采用单因素模型,CONVERGE样本与四个西方样本之间基于整体拟合指数观察到的MI水平,与西方样本之间观察到的水平非常相似。当将MI测试的双因素结构应用于针对体重、食欲、睡眠和精神运动变化分类的MD的14项诊断标准时,也获得了可比的结果。
尽管在语言、种族和文化方面存在差异,但MD的DSM标准在患有复发性MD的中国女性以及来自美国和欧洲的可比受试者中表现相似。MD的DSM标准可能评估的是对文化和种族差异相对不敏感的抑郁症状。这些结果支持了比较中国和西方国家抑郁症患者研究结果的努力。