Yim Gyeyoon, Ahn Younjhin, Chang Yoosoo, Ryu Seungho, Lim Joong-Yeon, Kang Danbee, Choi Eun-Kyung, Ahn Jiin, Choi Yuni, Cho Juhee, Park Hyun-Young
1Division of Cardiovascular and Rare Diseases, Korea National Institute of Health, Chungcheongbuk-do, Republic of Korea 2Department of Occupational and Environmental Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University College of Medicine, Seoul, Republic of Korea 3Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul, Republic of Korea 4Cancer Education Center, Samsung Comprehensive Cancer Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea 5Center for Cohort Studies, Total Healthcare Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Menopause. 2015 Oct;22(10):1108-16. doi: 10.1097/GME.0000000000000438.
The present study investigated the prevalence and severity of menopause symptoms experienced by Korean women aged 44 to 56 years and their associated factors.
A cross-sectional study was performed on 2,201 women aged 44 to 56 years in health checkup centers between November 2012 and March 2013. The 29-item Menopause-Specific Quality of Life Questionnaire was used to assess vasomotor, psychosocial, physical, and sexual symptoms related to menopause. The guidelines for the classification of reproductive aging stages proposed at the Stages of Reproductive Aging Workshop were used. Multivariable linear regression analyses were performed to identify factors associated with severity of menopause symptoms.
Among participants, 42.6% were premenopausal, 36.7% were perimenopausal, and 20.7% were postmenopausal. Although physical symptoms were the most severe menopause symptoms experienced by premenopausal and perimenopausal women, postmenopausal women reported sexual symptoms as the most bothersome. The mean scores for each domain increased from the premenopausal period through the postmenopausal period (P for trend < 0.001). The regression model revealed that age (for vasomotor and sexual symptoms) and obesity (for vasomotor and physical symptoms) were significantly associated with severity of menopause symptoms (P < 0.05). Physically active women had fewer severe physical symptoms related to menopause than inactive women.
Postmenopausal women experience the most severe symptoms. Obesity and physical activity are the main modifiable factors associated with symptom severity. Further studies are needed to examine the effects of physical activity promotion and weight control interventions on preventing menopause symptoms in Korean women.
本研究调查了44至56岁韩国女性更年期症状的患病率、严重程度及其相关因素。
2012年11月至2013年3月期间,在健康体检中心对2201名44至56岁的女性进行了一项横断面研究。采用29项更年期特异性生活质量问卷评估与更年期相关的血管舒缩、心理社会、身体和性症状。使用了生殖衰老研讨会提出的生殖衰老阶段分类指南。进行多变量线性回归分析以确定与更年期症状严重程度相关的因素。
参与者中,42.6%为绝经前,36.7%为围绝经期,20.7%为绝经后。尽管身体症状是绝经前和围绝经期女性经历的最严重的更年期症状,但绝经后女性报告性症状是最困扰的。每个领域的平均得分从绝经前期到绝经后期增加(趋势P<0.001)。回归模型显示,年龄(血管舒缩和性症状)和肥胖(血管舒缩和身体症状)与更年期症状严重程度显著相关(P<0.05)。身体活跃的女性与更年期相关的严重身体症状比不活跃的女性少。
绝经后女性经历的症状最严重。肥胖和身体活动是与症状严重程度相关的主要可改变因素。需要进一步研究来探讨促进身体活动和体重控制干预对预防韩国女性更年期症状的影响。