Graduate Program of Dentistry, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil.
Department of Pathology, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil ; Stomatology Clinic, University Hospital, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil.
J Oncol. 2015;2015:571739. doi: 10.1155/2015/571739. Epub 2015 Feb 15.
Dental treatment of patients with leukemia should be planned on the basis of antineoplastic therapy which can be chemotherapy with or without radiotherapy and bone marrow transplantation. Many are the oral manifestations presented by these patients, arising from leukemia and/or treatment. In addition, performing dental procedures at different stages of treatment (before, during, or after) must follow certain protocols in relation to the haematological indices of patients, aimed at maintaining health and contributing to the effectiveness of the results of antineoplastic therapy. Through a literature review, the purpose of this study was to report the hematological abnormalities present in patients with leukemia, trying to correlate them with the feasibility of dental treatment at different stages of the disease. It is concluded in this paper that dental treatment in relation to haematological indices presented by patients with leukemia must follow certain protocols, mainly related to neutrophil and platelet counts, and the presence of the dentist in a multidisciplinary team is required for the health care of this patient.
白血病患者的牙科治疗应根据抗肿瘤治疗方案进行规划,包括化疗联合或不联合放疗和骨髓移植。这些患者会出现许多口腔表现,这些表现可能源于白血病和/或治疗本身。此外,在治疗的不同阶段(治疗前、治疗中或治疗后)进行牙科操作时,必须遵循针对患者血液学指标的特定方案,以维持健康并有助于提高抗肿瘤治疗的效果。通过文献回顾,本研究旨在报告白血病患者存在的血液学异常,并尝试将其与疾病不同阶段牙科治疗的可行性进行关联。本文的结论是,针对白血病患者的血液学指标,牙科治疗必须遵循特定的方案,主要与中性粒细胞和血小板计数有关,并且需要牙医加入多学科团队,为这类患者提供医疗服务。