Elad Sharon, Raber-Durlacher Judith E, Brennan Michael T, Saunders Deborah P, Mank Arno P, Zadik Yehuda, Quinn Barry, Epstein Joel B, Blijlevens Nicole M A, Waltimo Tuomas, Passweg Jakob R, Correa M Elvira P, Dahllöf Göran, Garming-Legert Karin U E, Logan Richard M, Potting Carin M J, Shapira Michael Y, Soga Yoshihiko, Stringer Jacqui, Stokman Monique A, Vokurka Samuel, Wallhult Elisabeth, Yarom Noam, Jensen Siri Beier
Division of Oral Medicine, Eastman Institute for Oral Health, University of Rochester Medical Center, 625 Elmwood Ave., Rochester, NY, 14620, USA,
Support Care Cancer. 2015 Jan;23(1):223-36. doi: 10.1007/s00520-014-2378-x. Epub 2014 Sep 5.
Hematology-oncology patients undergoing chemotherapy and hematopoietic stem cell transplantation (HSCT) recipients are at risk for oral complications which may cause significant morbidity and a potential risk of mortality. This emphasizes the importance of basic oral care prior to, during and following chemotherapy/HSCT. While scientific evidence is available to support some of the clinical practices used to manage the oral complications, expert opinion is needed to shape the current optimal protocols.
This position paper was developed by members of the Oral Care Study Group, Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) and the European Society for Blood and Marrow Transplantation (EBMT) in attempt to provide guidance to the health care providers managing these patient populations.
The protocol on basic oral care outlined in this position paper is presented based on the following principles: prevention of infections, pain control, maintaining oral function, the interplay with managing oral complications of cancer treatment and improving quality of life.
Using these fundamental elements, we developed a protocol to assist the health care provider and present a practical approach for basic oral care. Research is warranted to provide robust scientific evidence and to enhance this clinical protocol.
接受化疗的血液肿瘤患者以及造血干细胞移植（HSCT）受者有发生口腔并发症的风险，这些并发症可能导致严重的发病率以及潜在的死亡风险。这凸显了化疗/HSCT之前、期间及之后进行基本口腔护理的重要性。虽然有科学证据支持一些用于处理口腔并发症的临床实践，但仍需要专家意见来制定当前的最佳方案。
本立场文件由口腔护理研究小组、癌症支持治疗多国协会/国际口腔肿瘤学会（MASCC/ISOO）以及欧洲血液和骨髓移植学会（EBMT）的成员共同制定，旨在为管理这些患者群体的医护人员提供指导。
本立场文件中概述的基本口腔护理方案基于以下原则提出：预防感染、控制疼痛、维持口腔功能、与癌症治疗口腔并发症管理的相互作用以及改善生活质量。
利用这些基本要素，我们制定了一个方案来协助医护人员，并为基本口腔护理提供一种实用方法。有必要开展研究以提供有力的科学证据并完善该临床方案。
