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50 岁以上女性中的癌症:关注吸烟问题。

Cancer in Women over 50 Years of Age: A Focus on Smoking.

机构信息

Department of Gynecology, State University of Campinas, Rua Alexander Fleming, 101, Cidade Universitária Zeferino Vaz, Campinas, São Paulo 13.083-881, Brazil.

Breast Clinic, Hospital for Maternal and Child Healthcare, Goiânia, Goiás 74.125-120, Brazil.

出版信息

Cancers (Basel). 2015 Mar 17;7(1):450-9. doi: 10.3390/cancers7010450.

Abstract

The increase in life expectancy worldwide has resulted in a greater prevalence of chronic non-communicable diseases. This study aims to evaluate the prevalence and factors associated with the occurrence of cancer among Brazilian women over the age of 50. A cross-sectional study with 622 women over the age of 50 was performed using a population survey. The outcome variable was the occurrence of a malignant tumor in any location. The independent variables were sociodemographic characteristics, self-perception of health, health-related habits and morbidities. Statistical analysis was carried out using the chi-square test and Poisson regression. The mean age of the women was 64.1 years. The prevalence of cancer was 6.8%. The main sites of occurrence of malignant tumors were the breast (31.9%), colorectal (12.7%) and skin (12.7%). In the final statistical model, the only factor associated with cancer was smoking > 15 cigarettes/day either currently or in the past: PR 2.03 (95% CI 1.06-3.89). The results have improved understanding of the prevalence and factors associated with cancer in Brazilian women aged 50 years or more. They should be encouraged to maintain a healthy lifestyle and pay particular attention to modifiable risk factors such as smoking.

摘要

全球预期寿命的增加导致慢性非传染性疾病的患病率上升。本研究旨在评估巴西 50 岁以上女性癌症发病的流行情况和相关因素。采用人群调查方法对 622 名 50 岁以上女性进行了一项横断面研究。结局变量为任何部位恶性肿瘤的发生。自变量为社会人口特征、自我健康感知、健康相关习惯和疾病。采用卡方检验和泊松回归进行统计分析。女性的平均年龄为 64.1 岁。癌症的患病率为 6.8%。恶性肿瘤发生的主要部位是乳房(31.9%)、结直肠(12.7%)和皮肤(12.7%)。在最终的统计模型中,唯一与癌症相关的因素是目前或曾经每天吸烟>15 支:PR 2.03(95%CI 1.06-3.89)。这些结果提高了对巴西 50 岁及以上女性癌症流行情况和相关因素的认识。应该鼓励她们保持健康的生活方式,并特别注意可改变的危险因素,如吸烟。

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本文引用的文献

1
Active cigarette smoking and the risk of breast cancer: a cohort study.主动吸烟与乳腺癌风险:一项队列研究。
Cancer Epidemiol. 2014 Aug;38(4):376-81. doi: 10.1016/j.canep.2014.05.007. Epub 2014 Jun 12.
3
Oncology in midlife and beyond.中年及以后的肿瘤学。
Climacteric. 2013 Oct;16(5):522-35. doi: 10.3109/13697137.2013.823539. Epub 2013 Aug 9.
10
Cigarette smoking and breast cancer risk: update of a prospective cohort study.吸烟与乳腺癌风险:一项前瞻性队列研究的更新
Breast Cancer Res Treat. 2006 Dec;100(3):293-9. doi: 10.1007/s10549-006-9255-3. Epub 2006 Jun 14.

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