[使用CD20单克隆抗体和抗病毒药物成功治疗重度丙型肝炎病毒相关性冷球蛋白血症性血管炎]
[Successful treatment of severe HCV-cryoglobulinemic vasculitis with the use of CD20 monoclonalantibodies and antiviral agents].
作者信息
Ignatova T M, Chernova O A, Burnevich E Z, Milovanova S Iu
出版信息
Klin Med (Mosk). 2014;92(8):62-4.
PMID:25790700
Abstract
This paper reports a case of successfuid treatment of severe HCV-cryoglobulinemic vasculitis with ulcerative necrotic skin lesions, digital necrosis, cryoglobulinemic glomnerulonephritis and sensorimotor neuropathy. Possibilities for the change of prognosis in the patients with HCV-cryoglobulinemic vasculitis are discussed along with the prospects for the improvement of antiviral and pathogenetic therapy.
摘要
本文报道了一例成功治疗的严重丙型肝炎病毒（HCV）冷球蛋白血症性血管炎患者，该患者伴有溃疡性坏死性皮肤病变、手指坏死、冷球蛋白血症性肾小球肾炎和感觉运动性神经病变。文中讨论了HCV冷球蛋白血症性血管炎患者预后改变的可能性以及抗病毒和病因治疗改善的前景。
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